ABCC9 and KCNJ8

Number of citations of the paper that reports this interaction (PubMedID 11136227)
33

Data Source:
HPRD (in vitro)

		ABCC9	KCNJ8
Description		ATP binding cassette subfamily C member 9	potassium inwardly rectifying channel subfamily J member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Inward Rectifying Potassium Channel Membrane Sarcomere Potassium Ion-transporting ATPase Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Potassium Ion-transporting ATPase Complex
	Molecular Function	Cation Channel Activity Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity Potassium Channel Regulator Activity ATPase Activity Cation-transporting ATPase Activity Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Ion Channel Binding	Inward Rectifier Potassium Channel Activity ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity Cation-transporting ATPase Activity Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Response To ATP Defense Response To Virus Transmembrane Transport Cardiac Conduction Potassium Ion Transmembrane Transport Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Potassium Ion Import Across Plasma Membrane
Pathways		ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia	ATP sensitive Potassium channels
Drugs		ATP Glyburide Nicorandil	Phenformin Levosimendan Glyburide Thiamylal Gliquidone Glisoxepide Yohimbine
Diseases		Atrial fibrillation
GWAS		Birth weight ( 27680694) Gout ( 22179738) Hippocampal sclerosis of aging ( 24770881) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653 30578418)	Birth weight ( 31043758)
Interacting Genes		6 interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA STX1A	4 interacting genes: ABCC8 ABCC9 KCNJ11 KCNJ2
Entrez ID		10060	3764
HPRD ID		03258	02962
Ensembl ID		ENSG00000069431	ENSG00000121361
Uniprot IDs		A0A024RAV7 O60706	A0A024RAV6 Q15842
PDB IDs
Enriched GO Terms of Interacting Partners?
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