DNAJB6 and BRMS1

Number of citations of the paper that reports this interaction (PubMedID 16919237)
34

Data Source:
HPRD (two hybrid, in vivo)

		DNAJB6	BRMS1
Description		DnaJ heat shock protein family (Hsp40) member B6	BRMS1 transcriptional repressor and anoikis regulator
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	ATPase Activator Activity DNA Binding Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Protein Folding Actin Cytoskeleton Organization Extracellular Matrix Organization Positive Regulation Of ATPase Activity Regulation Of Protein Localization Protein Localization To Nucleus Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways		Regulation of HSF1-mediated heat shock response	HDACs deacetylate histones
Drugs
Diseases
GWAS		Body mass index ( 28552196) Waist circumference ( 28552196)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		7 interacting genes: APP BRMS1 KRT18 MAP3K1 PIK3CA POLR1D USP8	48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		10049	25855
HPRD ID		07107	05879
Ensembl ID		ENSG00000105993	ENSG00000174744
Uniprot IDs		A0A0J9YX62 O75190	G5E9I4 Q9HCU9
PDB IDs		6U3R 6U3S	2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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