BRMS1 and ING1

Number of citations of the paper that reports this interaction (PubMedID 15451426)
31

Data Source:
HPRD (in vivo)

		BRMS1	ING1
Description		BRMS1 transcriptional repressor and anoikis regulator	inhibitor of growth family member 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Cell Cycle Negative Regulation Of Cell Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated
Pathways		HDACs deacetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)
Interacting Genes		48 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	28 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		25855	3621
HPRD ID		05879	03337
Ensembl ID		ENSG00000174744	ENSG00000153487
Uniprot IDs		G5E9I4 Q9HCU9	A0A0C4DFW2 Q9UK53
PDB IDs		2XUS 4AUV	2QIC
Enriched GO Terms of Interacting Partners?
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