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CLEC7A and BNIP3
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid)
CLEC7A
BNIP3
Description
C-type lectin domain containing 7A
BCL2 interacting protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Postsynaptic Density
Dendrite
Integral Component Of Mitochondrial Outer Membrane
Mitochondrial Membrane
Molecular Function
(1->3)-beta-D-glucan Binding
Protein Binding
Carbohydrate Binding
Pattern Recognition Receptor Activity
MHC Protein Binding
Metal Ion Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
Biological Process
Phagocytosis, Recognition
Inflammatory Response
Cell Recognition
Positive Regulation Of Cell Proliferation
Carbohydrate Mediated Signaling
Positive Regulation Of Gene Expression
Detection Of Fungus
Positive Regulation Of Cell Migration
Positive Regulation Of Protein Complex Assembly
Detection Of Molecule Of Fungal Origin
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Superoxide Anion Generation
T Cell Activation
Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process
Defense Response To Protozoan
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Interferon-gamma Biosynthetic Process
Positive Regulation Of Interleukin-10 Biosynthetic Process
Positive Regulation Of Interleukin-12 Biosynthetic Process
Positive Regulation Of Interleukin-2 Biosynthetic Process
Innate Immune Response
Positive Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of Interleukin-8 Biosynthetic Process
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Phagocytosis
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Killing Of Cells Of Other Organism
Positive Regulation Of Respiratory Burst
Cellular Response To Molecule Of Fungal Origin
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Positive Regulation Of Wound Healing
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Cell Maturation
Autophagy Of Mitochondrion
Response To Hypoxia
Apoptotic Process
Cell Death
Granzyme-mediated Apoptotic Signaling Pathway
Response To Bacterium
Positive Regulation Of Autophagy
Negative Regulation Of Mitochondrial Fusion
Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Necrotic Cell Death
Viral Process
Positive Regulation Of Macroautophagy
Cerebral Cortex Development
Mitochondrial Protein Catabolic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Protein Complex Disassembly
Mitochondrial Fragmentation Involved In Apoptotic Process
Negative Regulation Of Membrane Potential
Regulation Of Mitochondrial Membrane Permeability
Autophagic Cell Death
Response To Axon Injury
Oligodendrocyte Differentiation
Brown Fat Cell Differentiation
Neuron Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Defense Response To Virus
Response To Hyperoxia
Negative Regulation Of Cell Death
Cellular Response To Hydrogen Peroxide
Cellular Response To Mechanical Stimulus
Cellular Response To Cobalt Ion
Cellular Response To Hypoxia
Reactive Oxygen Species Metabolic Process
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Response To Oxygen-glucose Deprivation
Mitochondrial Outer Membrane Permeabilization
Toxin Transport
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Positive Regulation Of Autophagy Of Mitochondrion
Regulation Of Aerobic Respiration
Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
CLEC7A (Dectin-1) signaling
CLEC7A (Dectin-1) signaling
Drugs
Diseases
Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Metabolite levels (
23823483
)
Interacting Genes
19 interacting genes:
ADAM33
AIP
BNIP3
BNIP3L
CALM3
FAM3A
HSPD1
IL1RL1
JAGN1
KTN1
NINJ2
OCLN
PTTG1IP
RANBP9
RHOU
SMIM3
SYNE4
TMEM79
TMPRSS4
21 interacting genes:
BCL2
BCL2L1
BCL2L2
BNIP3L
CD47
CLEC7A
CLN8
CREB3
FATE1
HIF1A
HIVEP1
KTN1
LDLRAD1
LMNA
MAP1LC3B
NCBP1
OPA1
RHEB
TGM2
TMEM11
TUBGCP2
Entrez ID
64581
664
HPRD ID
08396
04482
Ensembl ID
ENSG00000172243
ENSG00000176171
Uniprot IDs
A0A024RAN9
A0A0S2Z5Q1
Q68D78
Q9BXN2
Q12983
Q6NVY4
PDB IDs
2J5D
2KA1
2KA2
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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