SPTB

Description		spectrin beta, erythrocytic
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GO Annotations	Cellular Component	Cytosol Spectrin Spectrin-associated Cytoskeleton Actin Cytoskeleton Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Protein-containing Complex
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Ankyrin Binding Actin Filament Binding
	Biological Process	MAPK Cascade ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Axon Guidance Actin Filament Capping
Pathways		NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade COPI-mediated anterograde transport
Drugs
Diseases		Hereditary elliptocytosis (HE) Hereditary spherocytosis (SPH)
GWAS		Daytime sleep phenotypes ( 27126917) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Obesity-related traits ( 23251661) Pediatric areal bone mineral density (radius) ( 28181694) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Type 2 diabetes ( 31049640)
Interacting Genes		14 interacting genes: ACTB ADD1 ANK1 AP1G1 CSRP3 DMTN EPB41 MAPT NCAM1 SH2D2A SPTA1 SPTAN1 STAT1 YWHAQ
Entrez ID		6710
HPRD ID		01686
Ensembl ID		ENSG00000070182
Uniprot IDs		P11277
PDB IDs		1S35 3EDU 3F57 3KBT 3KBU 3LBX
Enriched GO Terms of Interacting Partners?
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