| Novel |
ADRB3
|
adrenoceptor beta 3 |
- Adrenoceptors
- G alpha (s) signalling events
|
- Amphetamine
- Bethanidine
- Metoprolol
- Dihydroergotamine
- Olanzapine
- Norepinephrine
- Nortriptyline
- Propranolol
- Paroxetine
- Trimipramine
- Cryptenamine
- Alprenolol
- Ritodrine
- Terbutaline
- Salmeterol
- Pindolol
- Formoterol
- Salbutamol
- Ergoloid mesylate
- Isoprenaline
- Arbutamine
- Amiodarone
- Fenoterol
- Ephedra sinica root
- Mephentermine
- Clenbuterol
- Oxprenolol
- Celiprolol
- Nebivolol
- Amibegron
- Solabegron
- Droxidopa
- Bufuralol
- Bopindolol
- Bupranolol
- Mirabegron
- Racepinephrine
- Dihydroergocornine
- DL-Methylephedrine
- Dihydroergocristine
- Vibegron
|
|
| Novel |
DCTN6
|
dynactin subunit 6 |
- MHC class II antigen presentation
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- COPI-mediated anterograde transport
- COPI-independent Golgi-to-ER retrograde traffic
|
|
|
| Novel |
LINC03042
|
long intergenic non-protein coding RNA 3042 |
|
|
|
| Novel |
RBPMS
|
RNA binding protein, mRNA processing factor |
|
|
|
| Novel |
SFRP1
|
secreted frizzled related protein 1 |
- TCF dependent signaling in response to WNT
- Negative regulation of TCF-dependent signaling by WNT ligand antagonists
|
|
|
| Novel |
WRN
|
WRN RecQ like helicase |
- Processive synthesis on the C-strand of the telomere
- Removal of the Flap Intermediate from the C-strand
- SUMOylation of DNA damage response and repair proteins
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Homologous DNA Pairing and Strand Exchange
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
- Defective homologous recombination repair (HRR) due to BRCA1 loss of function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
- Impaired BRCA2 binding to RAD51
- Impaired BRCA2 binding to PALB2
|
|
- Defects in RecQ helicases, including: Bloom's syndrome; Werner's syndrome; Rothmund-Thomson syndrome
|
|
AQP6
|
aquaporin 6 |
- Passive transport by Aquaporins
|
|
|
|
GJA8
|
gap junction protein alpha 8 |
|
|
|
|
HSD17B13
|
hydroxysteroid 17-beta dehydrogenase 13 |
- Lipid particle organization
|
|
|
|
MEOX2
|
mesenchyme homeobox 2 |
|
|
|
|
PGRMC2
|
progesterone receptor membrane component 2 |
- RHOA GTPase cycle
- RAC2 GTPase cycle
- RHOD GTPase cycle
- RHOG GTPase cycle
- RAC3 GTPase cycle
- Heme signaling
|
|
|
|
SPCS1
|
signal peptidase complex subunit 1 |
- SRP-dependent cotranslational protein targeting to membrane
- Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
- Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
- Synthesis, secretion, and deacylation of Ghrelin
- Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
- Maturation of hRSV A proteins
|
|
|
|
TMEM14B
|
transmembrane protein 14B |
|
|
|