SELENOS - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	BLZF1	basic leucine zipper nuclear factor 1	Golgi Cisternae Pericentriolar Stack Reorganization
Novel	CD180	CD180 molecule	Toll Like Receptor 4 (TLR4) Cascade
Novel	CELF4	CUGBP Elav-like family member 4
Novel	EIF2AK1	eukaryotic translation initiation factor 2 alpha kinase 1	Response of EIF2AK1 (HRI) to heme deficiency Cellular response to mitochondrial stress	Fostamatinib
Novel	ETV7	ETS variant transcription factor 7
Novel	LIMK1	LIM domain kinase 1	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling Sema3A PAK dependent Axon repulsion Sema3A PAK dependent Axon repulsion Sema4D induced cell migration and growth-cone collapse RHO GTPases Activate ROCKs RHO GTPases activate PAKs	Dabrafenib Fostamatinib
Novel	LINS1	lines homolog 1
Novel	LRRK1	leucine rich repeat kinase 1
Novel	NCBP1	nuclear cap binding protein subunit 1	SLBP independent Processing of Histone Pre-mRNAs Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Abortive elongation of HIV-1 transcript in the absence of Tat snRNP Assembly RNA Polymerase II Pre-transcription Events FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Processing of Intronless Pre-mRNAs Signaling by FGFR2 IIIa TM Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Nuclear RNA decay
Novel	OR4F4	olfactory receptor family 4 subfamily F member 4
Novel	SNRPA1	small nuclear ribonucleoprotein polypeptide A'	mRNA Splicing - Major Pathway Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Novel	SYNM	synemin
Novel	TARS3	threonyl-tRNA synthetase 3
Novel	TM2D3	TM2 domain containing 3
Novel	TTC23	tetratricopeptide repeat domain 23
Novel	ZBTB33	zinc finger and BTB domain containing 33	Negative Regulation of CDH1 Gene Transcription
	APOA5	apolipoprotein A5	PPARA activates gene expression Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Assembly of active LPL and LIPC lipase complexes Chylomicron remodeling		Hyperlipoproteinemia, type V
	DERL1	derlin 1	ABC-family proteins mediated transport N-glycan trimming in the ER and Calnexin/Calreticulin cycle Defective CFTR causes cystic fibrosis E3 ubiquitin ligases ubiquitinate target proteins AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
	GTF2IRD1	GTF2I repeat domain containing 1
	KLHDC2	kelch domain containing 2

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