SELENOS and LINS1

		SELENOS	LINS1
Description		selenoprotein S	lines homolog 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Plasma Membrane Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Derlin-1-VIMP Complex Derlin-1 Retrotranslocation Complex
	Molecular Function	Protein Binding Antioxidant Activity Enzyme Binding Signaling Receptor Activity ATPase Binding Ubiquitin-specific Protease Binding
	Biological Process	Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Gluconeogenesis Intracellular Protein Transport ER Overload Response Response To Glucose Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Cellular Response To Insulin Stimulus Cellular Response To Oxidative Stress ERAD Pathway Establishment Of Protein Localization Cell Redox Homeostasis Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of D-glucose Import Negative Regulation Of Inflammatory Response Response To Redox State Cellular Response To Lipopolysaccharide Regulation Of Nitric Oxide Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Macrophage Apoptotic Process	Cognition
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: APOA5 DERL1 GTF2IRD1 KLHDC2 KPNB1 MFHAS1 SAA1 SRPK2 VCP	1 interacting genes: CLK1
Entrez ID		55829	55180
HPRD ID		12133	17280
Ensembl ID		ENSG00000131871	ENSG00000140471
Uniprot IDs		Q6GYA4 Q9BQE4	Q8NG48
PDB IDs		2Q2F 5KIU 5KIY 6DO4
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Spliceosomal Complex Assembly Derlin-1 Retrotranslocation Complex Cellular Response To Misfolded Protein Response To Misfolded Protein Protein-RNA Complex Assembly Retrograde Protein Transport, ER To Cytosol MHC Class I Protein Binding Ubiquitin-specific Protease Binding High-density Lipoprotein Particle Regulation Of MRNA Splicing, Via Spliceosome Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Topologically Incorrect Protein	Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway ER Overload Response Very-low-density Lipoprotein Particle Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Acute Inflammatory Response Negative Regulation Of D-glucose Transmembrane Transport Negative Regulation Of Glycogen Biosynthetic Process Low-density Lipoprotein Particle Regulation Of Acute Inflammatory Response To Antigenic Stimulus Ubiquitin-specific Protease Binding Derlin-1 Retrotranslocation Complex Negative Regulation Of Macrophage Apoptotic Process Negative Regulation Of D-glucose Import Negative Regulation Of Myeloid Cell Apoptotic Process Derlin-1-VIMP Complex Response To Redox State Antioxidant Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Exit From Endoplasmic Reticulum Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Myeloid Cell Apoptotic Process Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway ER-nucleus Signaling Pathway Regulation Of Glycogen Metabolic Process Non-membrane Spanning Protein Tyrosine Kinase Activity Cell Redox Homeostasis Regulation Of Acute Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Response To Endoplasmic Reticulum Stress Cytoplasmic Microtubule Regulation Of Gluconeogenesis Negative Regulation Of Leukocyte Apoptotic Process Regulation Of D-glucose Import Negative Regulation Of Tumor Necrosis Factor Production Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Nitric Oxide Metabolic Process Regulation Of D-glucose Transmembrane Transport Cellular Oxidant Detoxification ATPase Binding Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Insulin Stimulus ERAD Pathway Regulation Of Glucose Metabolic Process Cellular Detoxification Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transmembrane Transport Response To Glucose
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