| Novel |
AIMP2
|
aminoacyl tRNA synthetase complex interacting multifunctional protein 2 |
- Selenoamino acid metabolism
- Cytosolic tRNA aminoacylation
- Transcriptional and post-translational regulation of MITF-M expression and activity
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| Novel |
ANXA5
|
annexin A5 |
|
- Fluocinolone acetonide
- L-Alpha-Glycerophosphorylserine
- L-thioproline
- K201 free base
- sn-glycero-3-phosphoethanolamine
- 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
- N,O6-Disulfo-Glucosamine
- 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
- Copper
|
|
| Novel |
CCND2
|
cyclin D2 |
- Cyclin D associated events in G1
- Regulation of RUNX1 Expression and Activity
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
- Drug-mediated inhibition of CDK4/CDK6 activity
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|
|
| Novel |
CHERP
|
calcium homeostasis endoplasmic reticulum protein |
- mRNA Splicing - Major Pathway
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|
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| Novel |
CHST12
|
carbohydrate sulfotransferase 12 |
|
|
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| Novel |
FSCN1
|
fascin actin-bundling protein 1 |
- Interleukin-4 and Interleukin-13 signaling
|
|
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| Novel |
HOXA10
|
homeobox A10 |
|
|
|
| Novel |
NXPH1
|
neurexophilin 1 |
|
|
|
| Novel |
PIN4
|
peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
|
|
|
| Novel |
PRKAR1B
|
protein kinase cAMP-dependent type I regulatory subunit beta |
- PKA activation
- PKA activation in glucagon signalling
- DARPP-32 events
- Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
- Vasopressin regulates renal water homeostasis via Aquaporins
- CREB1 phosphorylation through the activation of Adenylate Cyclase
- Hedgehog 'off' state
- GPER1 signaling
- ADORA2B mediated anti-inflammatory cytokines production
- FCGR3A-mediated IL10 synthesis
- Factors involved in megakaryocyte development and platelet production
- High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
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|
|
| Novel |
RPA3
|
replication protein A3 |
- Translesion synthesis by REV1
- Recognition of DNA damage by PCNA-containing replication complex
- Translesion Synthesis by POLH
- Removal of the Flap Intermediate from the C-strand
- Activation of ATR in response to replication stress
- Regulation of HSF1-mediated heat shock response
- HSF1 activation
- Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- PCNA-Dependent Long Patch Base Excision Repair
- Translesion synthesis by POLK
- Translesion synthesis by POLI
- Termination of translesion DNA synthesis
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Formation of Incision Complex in GG-NER
- Gap-filling DNA repair synthesis and ligation in GG-NER
- Dual Incision in GG-NER
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Fanconi Anemia Pathway
- Regulation of TP53 Activity through Phosphorylation
- Activation of the pre-replicative complex
- Removal of the Flap Intermediate
- G2/M DNA damage checkpoint
- Meiotic recombination
- Impaired BRCA2 binding to RAD51
|
|
|
| Novel |
S100P
|
S100 calcium binding protein P |
|
|
|
| Novel |
STAM
|
signal transducing adaptor molecule |
- EGFR downregulation
- Metalloprotease DUBs
- Negative regulation of MET activity
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- InlB-mediated entry of Listeria monocytogenes into host cell
- RHOU GTPase cycle
- Endosomal Sorting Complex Required For Transport (ESCRT)
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|
|
| Novel |
TTYH3
|
tweety family member 3 |
|
|
|
| Novel |
TULP4
|
TUB like protein 4 |
|
|
|
|
ALOX5
|
arachidonate 5-lipoxygenase |
- Synthesis of 5-eicosatetraenoic acids
- Synthesis of Leukotrienes (LT) and Eoxins (EX)
- Biosynthesis of Lipoxins (LX)
- Interleukin-4 and Interleukin-13 signaling
- Neutrophil degranulation
- Interleukin-18 signaling
- Biosynthesis of D-series resolvins
- Biosynthesis of maresins
- Biosynthesis of E-series 18(S)-resolvins
- Biosynthesis of aspirin-triggered D-series resolvins
- Biosynthesis of E-series 18(R)-resolvins
- Biosynthesis of DPAn-3-derived protectins and resolvins
- Biosynthesis of DPAn-3-derived maresins
- Biosynthesis of DPAn-3-derived 13-series resolvins
- Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives
|
- Icosapent
- Vitamin E
- Masoprocol
- Aminosalicylic acid
- Mesalazine
- Montelukast
- Diethylcarbamazine
- Zileuton
- Sulfasalazine
- Meclofenamic acid
- Balsalazide
- Minocycline
- Hyperforin
- Resveratrol
- Licofelone
- MLN-977
- Morniflumate
- Diacerein
- Fostamatinib
- Rhein
- alpha-Tocopherol succinate
- D-alpha-Tocopherol acetate
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AMOTL2
|
angiomotin like 2 |
|
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|
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ATG5
|
autophagy related 5 |
- Macroautophagy
- PINK1-PRKN Mediated Mitophagy
- Receptor Mediated Mitophagy
- Negative regulators of DDX58/IFIH1 signaling
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|
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BIRC2
|
baculoviral IAP repeat containing 2 |
- Apoptotic cleavage of cellular proteins
- NOD1/2 Signaling Pathway
- TICAM1, RIP1-mediated IKK complex recruitment
- RIPK1-mediated regulated necrosis
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- TNFR2 non-canonical NF-kB pathway
- Regulation of necroptotic cell death
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Ub-specific processing proteases
- IKK complex recruitment mediated by RIP1
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|
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CAPN7
|
calpain 7 |
- Degradation of the extracellular matrix
|
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