Search Results for: KRT6A

49 interactions involving KRT6A - keratin 6A found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel CCR1 C-C motif chemokine receptor 1
  • Chemokine receptors bind chemokines
  • G alpha (i) signalling events
  • Interleukin-10 signaling
Novel GNL1 G protein nucleolar 1 (putative)
Novel KRT1 keratin 1
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
  • Zinc
  • Copper
  • Zinc acetate
  • Ichthyosis hystrix, Curth-Macklin type
  • Epidermolytic palmoplantar keratoderma (EPPK)
  • Striate palmoplantar keratoderma
  • Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
Novel KRT3 keratin 3
  • Keratinization
  • Formation of the cornified envelope
  • Meesmann corneal dystrophy
Novel KRT4 keratin 4
  • Keratinization
  • Formation of the cornified envelope
  • White sponge nevus
Novel KRT5 keratin 5
  • Type I hemidesmosome assembly
  • Keratinization
  • Formation of the cornified envelope
  • Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
  • Developmental Lineage of Mammary Gland Luminal Epithelial Cells
  • Developmental Lineage of Mammary Gland Myoepithelial Cells
  • Developmental Lineage of Mammary Stem Cells
  • Zinc
  • Zinc acetate
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
  • Dowling-Degos disease
Novel KRT6B keratin 6B
  • Keratinization
  • Formation of the cornified envelope
  • Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
Novel KRT7 keratin 7
  • Keratinization
  • Formation of the cornified envelope
  • Developmental Lineage of Pancreatic Ductal Cells
  • Primaquine
  • Verpasep caltespen
Novel PRPH peripherin
  • Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
Novel RND1 Rho family GTPase 1
  • SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
  • Sema4D mediated inhibition of cell attachment and migration
  • Sema4D induced cell migration and growth-cone collapse
  • RND1 GTPase cycle
Novel TARBP2 TARBP2 subunit of RISC loading complex
  • MicroRNA (miRNA) biogenesis
  • Small interfering RNA (siRNA) biogenesis
  • PKR-mediated signaling
Novel TMBIM6 transmembrane BAX inhibitor motif containing 6
BEX2 brain expressed X-linked 2
CCDC85B coiled-coil domain containing 85B
DSP desmoplakin
  • Apoptotic cleavage of cell adhesion proteins
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • RND3 GTPase cycle
  • RND1 GTPase cycle
  • Zinc
  • Artenimol
  • Zinc acetate
  • Striate palmoplantar keratoderma
  • Skin fragility-woolly hair syndrome
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Naxos disease and Carvajal syndrome
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GEM GTP binding protein overexpressed in skeletal muscle
  • NPAS4 regulates expression of target genes
GOLGA2 golgin A2
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • COPII-mediated vesicle transport
  • COPI-mediated anterograde transport
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
  • EGFR downregulation
  • Lysosome Vesicle Biogenesis
  • Ub-specific processing proteases
  • Negative regulation of MET activity
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • InlB-mediated entry of Listeria monocytogenes into host cell
  • RHOU GTPase cycle
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • Inhibition of membrane repair
  • Prevention of phagosomal-lysosomal fusion
  • RHOBTB3 ATPase cycle
  • Citric acid
KDM1A lysine demethylase 1A
  • HDACs deacetylate histones
  • HDMs demethylate histones
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Regulation of PTEN gene transcription
  • Estrogen-dependent gene expression
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • Potential therapeutics for SARS
  • Negative Regulation of CDH1 Gene Transcription
  • Factors involved in megakaryocyte development and platelet production
  • Vafidemstat
KIFC3 kinesin family member C3

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