| Novel |
DHX57
|
DExH-box helicase 57 |
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| Novel |
GTF2A1
|
general transcription factor IIA subunit 1 |
- HIV Transcription Initiation
- RNA Polymerase II HIV Promoter Escape
- Transcription of the HIV genome
- RNA Polymerase II Pre-transcription Events
- RNA polymerase II transcribes snRNA genes
- RNA polymerase II transcribes snRNA genes
- RNA Polymerase II Promoter Escape
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
- RNA Polymerase II Transcription Initiation
- RNA Polymerase II Transcription Initiation And Promoter Clearance
- Estrogen-dependent gene expression
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| Novel |
MAP4K3
|
mitogen-activated protein kinase kinase kinase kinase 3 |
|
|
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| Novel |
NRG2
|
neuregulin 2 |
- Signaling by ERBB2
- Signaling by ERBB4
- Signaling by ERBB4
- SHC1 events in ERBB2 signaling
- SHC1 events in ERBB2 signaling
- PI3K events in ERBB4 signaling
- SHC1 events in ERBB4 signaling
- Nuclear signaling by ERBB4
- PIP3 activates AKT signaling
- GRB7 events in ERBB2 signaling
- Downregulation of ERBB2:ERBB3 signaling
- GRB2 events in ERBB2 signaling
- PI3K events in ERBB2 signaling
- Constitutive Signaling by Aberrant PI3K in Cancer
- RAF/MAP kinase cascade
- ERBB2 Regulates Cell Motility
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- ERBB2 Activates PTK6 Signaling
- Downregulation of ERBB2 signaling
- Signaling by ERBB2 KD Mutants
- Signaling by ERBB2 TMD/JMD mutants
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|
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| Novel |
OTOF
|
otoferlin |
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Sensory processing of sound by inner hair cells of the cochlea
|
|
- Deafness, autosomal recessive
|
| Novel |
PRSS8
|
serine protease 8 |
- Formation of the cornified envelope
|
- 1-[4-(hydroxymethyl)phenyl]guanidine
|
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| Novel |
SRSF7
|
serine and arginine rich splicing factor 7 |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA Splicing - Minor Pathway
- mRNA 3'-end processing
- Processing of Capped Intron-Containing Pre-mRNA
- RNA Polymerase II Transcription Termination
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|
|
| Novel |
TMEM178A
|
transmembrane protein 178A |
|
|
|
| Novel |
TRIM29
|
tripartite motif containing 29 |
- Interferon gamma signaling
|
|
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| Novel |
ZNF311
|
zinc finger protein 311 |
- Generic Transcription Pathway
|
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ADAMTSL4
|
ADAMTS like 4 |
- Defective B3GALTL causes PpS
- O-glycosylation of TSR domain-containing proteins
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|
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ATXN1
|
ataxin 1 |
|
|
- Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
|
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BANP
|
BTG3 associated nuclear protein |
- Regulation of TP53 Activity through Association with Co-factors
- Degradation of CDH1
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|
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BARD1
|
BRCA1 associated RING domain 1 |
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- UCH proteinases
- Metalloprotease DUBs
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Nonhomologous End-Joining (NHEJ)
- Homologous DNA Pairing and Strand Exchange
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
- Defective DNA double strand break response due to BRCA1 loss of function
- Defective DNA double strand break response due to BARD1 loss of function
- Defective homologous recombination repair (HRR) due to BRCA1 loss of function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
- Impaired BRCA2 binding to RAD51
- Impaired BRCA2 binding to PALB2
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BCAS2
|
BCAS2 pre-mRNA processing factor |
- mRNA Splicing - Major Pathway
|
|
|
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BHLHE40
|
basic helix-loop-helix family member e40 |
- BMAL1:CLOCK,NPAS2 activates circadian expression
- Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
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BOLL
|
boule RNA binding protein |
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CALCOCO2
|
calcium binding and coiled-coil domain 2 |
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CEBPA
|
CCAAT enhancer binding protein alpha |
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
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- Acute myeloid leukemia (AML)
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DAB1
|
DAB adaptor protein 1 |
- Reelin signalling pathway
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