| Novel |
CCL24
|
C-C motif chemokine ligand 24 |
|
|
|
| Novel |
LAT2
|
linker for activation of T cells family member 2 |
- Role of LAT2/NTAL/LAB on calcium mobilization
- Role of LAT2/NTAL/LAB on calcium mobilization
|
|
|
| Novel |
PTPN12
|
protein tyrosine phosphatase non-receptor type 12 |
- SHC1 events in ERBB2 signaling
- SHC1 events in ERBB2 signaling
- EGFR downregulation
- Signaling by PDGF
- Downregulation of ERBB2 signaling
- Interleukin-37 signaling
- Constitutive Signaling by Overexpressed ERBB2
|
|
|
| Novel |
RFC2
|
replication factor C subunit 2 |
- Translesion synthesis by REV1
- Recognition of DNA damage by PCNA-containing replication complex
- Translesion Synthesis by POLH
- Polymerase switching on the C-strand of the telomere
- Activation of ATR in response to replication stress
- PCNA-Dependent Long Patch Base Excision Repair
- Translesion synthesis by POLK
- Translesion synthesis by POLI
- Termination of translesion DNA synthesis
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Gap-filling DNA repair synthesis and ligation in GG-NER
- Dual Incision in GG-NER
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Regulation of TP53 Activity through Phosphorylation
- Polymerase switching
- G2/M DNA damage checkpoint
- Impaired BRCA2 binding to RAD51
|
|
|
| Novel |
STT3B
|
STT3 oligosaccharyltransferase complex catalytic subunit B |
- Asparagine N-linked glycosylation
- Maturation of spike protein
- Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition
- PD-L1(CD274) glycosylation and translocation to plasma membrane
|
|
|
|
C11orf68
|
chromosome 11 open reading frame 68 |
|
|
|
|
CEBPA
|
CCAAT enhancer binding protein alpha |
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
|
|
- Acute myeloid leukemia (AML)
|
|
DDIT4L
|
DNA damage inducible transcript 4 like |
|
|
|
|
DLG3
|
discs large MAGUK scaffold protein 3 |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- NrCAM interactions
- Activation of Ca-permeable Kainate Receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Synaptic adhesion-like molecules
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
|
- Non-syndromic X-linked mental retardation
|
|
FBXO17
|
F-box protein 17 |
- Neddylation
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
LNX1
|
ligand of numb-protein X 1 |
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
PICK1
|
protein interacting with PRKCA 1 |
- Cell surface interactions at the vascular wall
- Trafficking of GluR2-containing AMPA receptors
|
|
|
|
SPG21
|
SPG21 abhydrolase domain containing, maspardin |
|
|
- Hereditary spastic paraplegia (SPG)
|