| Novel |
ATL1
|
atlastin GTPase 1 |
|
|
- Hereditary spastic paraplegia (SPG)
|
| Novel |
L2HGDH
|
L-2-hydroxyglutarate dehydrogenase |
- Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
|
|
|
| Novel |
TMX1
|
thioredoxin related transmembrane protein 1 |
|
|
|
| Novel |
TRIM9
|
tripartite motif containing 9 |
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
APP
|
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
HMGB1
|
high mobility group box 1 |
- ER-Phagosome pathway
- Apoptosis induced DNA fragmentation
- MyD88:MAL(TIRAP) cascade initiated on plasma membrane
- TAK1-dependent IKK and NF-kappa-B activation
- MyD88 deficiency (TLR2/4)
- IRAK4 deficiency (TLR2/4)
- Pyroptosis
- Regulation of TLR by endogenous ligand
- Neutrophil degranulation
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- TRAF6 mediated NF-kB activation
|
- Chloroquine
- Ethyl pyruvate
|
|
|
RNF10
|
ring finger protein 10 |
|
|
|