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Novel |
MRRF |
mitochondrial ribosome recycling factor |
- Mitochondrial translation termination
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Novel |
PHF19 |
PHD finger protein 19 |
- PRC2 methylates histones and DNA
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ABCA2 |
ATP binding cassette subfamily A member 2 |
- ABC transporters in lipid homeostasis
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CDK5 |
cyclin dependent kinase 5 |
- DARPP-32 events
- CRMPs in Sema3A signaling
- CRMPs in Sema3A signaling
- Regulation of TP53 Activity through Phosphorylation
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- NGF-stimulated transcription
- Activated NTRK2 signals through CDK5
- NPAS4 regulates expression of target genes
- Factors involved in megakaryocyte development and platelet production
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
- Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK
- Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
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- Indirubin-3'-monoxime
- Olomoucine
- Hymenialdisine
- SU9516
- Alvocidib
- Alsterpaullone
- 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
- Trilaciclib
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CDK5R1 |
cyclin dependent kinase 5 regulatory subunit 1 |
- CRMPs in Sema3A signaling
- CRMPs in Sema3A signaling
- Regulation of TP53 Activity through Phosphorylation
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- NGF-stimulated transcription
- NGF-stimulated transcription
- Activated NTRK2 signals through CDK5
- NPAS4 regulates expression of target genes
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- Indirubin-3'-monoxime
- 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
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CLIP4 |
CAP-Gly domain containing linker protein family member 4 |
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CRMP1 |
collapsin response mediator protein 1 |
- CRMPs in Sema3A signaling
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EEF1G |
eukaryotic translation elongation factor 1 gamma |
- Eukaryotic Translation Elongation
- Signaling by ALK fusions and activated point mutants
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ERG28 |
ergosterol biosynthesis 28 homolog |
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FBXO25 |
F-box protein 25 |
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HAP1 |
huntingtin associated protein 1 |
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KAT5 |
lysine acetyltransferase 5 |
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- DNA Damage/Telomere Stress Induced Senescence
- HATs acetylate histones
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Sensing of DNA Double Strand Breaks
- Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Nonhomologous End-Joining (NHEJ)
- Homologous DNA Pairing and Strand Exchange
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Regulation of TP53 Activity through Phosphorylation
- G2/M DNA damage checkpoint
- Estrogen-dependent gene expression
- Defective homologous recombination repair (HRR) due to BRCA1 loss of function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
- Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
- Impaired BRCA2 binding to RAD51
- Impaired BRCA2 binding to PALB2
- Cardiogenesis
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- Coenzyme A
- S-Acetyl-Cysteine
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LRRK1 |
leucine rich repeat kinase 1 |
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LUC7L2 |
LUC7 like 2, pre-mRNA splicing factor |
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MAGEH1 |
MAGE family member H1 |
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MAPRE1 |
microtubule associated protein RP/EB family member 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- EML4 and NUDC in mitotic spindle formation
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NEFL |
neurofilament light chain |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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- Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
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PCBD1 |
pterin-4 alpha-carbinolamine dehydratase 1 |
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- L-erythro-7,8-dihydrobiopterin
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- Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
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PTN |
pleiotrophin |
- Signaling by ALK
- Signaling by ALK
- MDK and PTN in ALK signaling
- MDK and PTN in ALK signaling
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RBM48 |
RNA binding motif protein 48 |
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