NIF3L1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
NOL3	nucleolar protein 3
NUDT14	nudix hydrolase 14	Synthesis of dolichyl-phosphate-glucose
NUDT21	nudix hydrolase 21	mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
ORC5	origin recognition complex subunit 5	E2F-enabled inhibition of pre-replication complex formation Activation of ATR in response to replication stress Assembly of the ORC complex at the origin of replication CDC6 association with the ORC:origin complex Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex
PAFAH1B3	platelet activating factor acetylhydrolase 1b catalytic subunit 3	COPI-independent Golgi-to-ER retrograde traffic	(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
PAICS	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	Purine ribonucleoside monophosphate biosynthesis	Aspartic acid
PCBD1	pterin-4 alpha-carbinolamine dehydratase 1	Phenylalanine metabolism	L-erythro-7,8-dihydrobiopterin	Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
PNMA1	PNMA family member 1
POLR1C	RNA polymerase I and III subunit C	Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter		Treacher Collins syndrome
PPIH	peptidylprolyl isomerase H	mRNA Splicing - Major Pathway SARS-CoV-1 activates/modulates innate immune responses	Proline
PRTFDC1	phosphoribosyl transferase domain containing 1
PTPA	protein phosphatase 2 phosphatase activator
RABAC1	Rab acceptor 1
RAD54B	RAD54 homolog B
RPIA	ribose 5-phosphate isomerase A	RPIA deficiency: failed conversion of R5P to RU5P RPIA deficiency: failed conversion of RU5P to R5P Pentose phosphate pathway	4-phospho-L-threonic acid
S100A1	S100 calcium binding protein A1	ER-Phagosome pathway MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) Regulation of TLR by endogenous ligand	Olopatadine
SAT1	spermidine/spermine N1-acetyltransferase 1	Interconversion of polyamines	N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine	Keratosis follicularis spinulosa decalvans
SEPTIN1	septin 1
SNF8	SNF8 subunit of ESCRT-II	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
SPG21	SPG21 abhydrolase domain containing, maspardin			Hereditary spastic paraplegia (SPG)

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