CYB5R3 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
SPP1	secreted phosphoprotein 1	Degradation of the extracellular matrix Signaling by PDGF Integrin cell surface interactions Integrin cell surface interactions Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) RUNX3 Regulates Immune Response and Cell Migration Post-translational protein phosphorylation Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
STOM	stomatin	Stimuli-sensing channels Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOJ GTPase cycle		Hereditary stomatocytosis (HSt); Dehydrated hereditary stomatocytosis (DHS); Overhydrated hereditary stomatocytosis (OHS); Familial pseudohyperkalemia (FP)
TMEM115	transmembrane protein 115	COPI-mediated anterograde transport
TMEM147	transmembrane protein 147
TMEM14B	transmembrane protein 14B
TMEM14C	transmembrane protein 14C
TMEM201	transmembrane protein 201
TMEM31	transmembrane protein 31
TMEM51	transmembrane protein 51
TMEM60	transmembrane protein 60
TMEM79	transmembrane protein 79
TNF	tumor necrosis factor	Transcriptional regulation of white adipocyte differentiation TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway TNFR1-mediated ceramide production TNFR2 non-canonical NF-kB pathway Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling TNF signaling Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	Etanercept Adalimumab Infliximab Chloroquine Epinephrine Pseudoephedrine Clenbuterol Pranlukast Amrinone Trichostatin A Afelimomab YSIL6 SD118 PN0621 OMS-103HP Talmapimod VX-702 Atiprimod CRx-139 CYT007-TNFQb Andrographolide Ethyl pyruvate AME-527 PR-104 Plinabulin Dexanabinol Onercept Golimumab Certolizumab pegol Pomalidomide Polaprezinc Foreskin fibroblast (neonatal) Foreskin keratinocyte (neonatal) Bryostatin 1 Binimetinib Dilmapimod Glycyrrhizic acid	Graft-versus-host disease Systemic lupus erythematosus Allograft rejection Asthma
TNFRSF10C	TNF receptor superfamily member 10c	TP53 Regulates Transcription of Death Receptors and Ligands
UBIAD1	UbiA prenyltransferase domain containing 1	Metabolism of vitamin K		Schnyder corneal dystrophy (SCD); Schnyder crystalline corneal dystrophy (SCCD); Crystalline stromal dystrophy; Schnyder crystalline dystrophy sine crystals
UNC50	unc-50 inner nuclear membrane RNA binding protein
UNC93B1	unc-93B1 regulator of TLR signaling	Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
UPK1B	uroplakin 1B
UPK2	uroplakin 2
VAMP1	vesicle associated membrane protein 1	Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type G (botG)	Botulinum toxin type B
VAMP4	vesicle associated membrane protein 4	Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis

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