|
LNPEP
|
leucyl and cystinyl aminopeptidase |
- Endosomal/Vacuolar pathway
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase |
- GPVI-mediated activation cascade
- Signaling by SCF-KIT
- Signaling by SCF-KIT
- Regulation of KIT signaling
- Cell surface interactions at the vascular wall
- FCGR activation
- PECAM1 interactions
- Fc epsilon receptor (FCERI) signaling
- Fc epsilon receptor (FCERI) signaling
- EPH-Ephrin signaling
- Role of LAT2/NTAL/LAB on calcium mobilization
- Role of LAT2/NTAL/LAB on calcium mobilization
- FCERI mediated MAPK activation
- FCERI mediated Ca+2 mobilization
- FCERI mediated Ca+2 mobilization
- FCERI mediated NF-kB activation
- Co-stimulation by CD28
- Co-inhibition by CTLA4
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- EPHA-mediated growth cone collapse
- EPHA-mediated growth cone collapse
- EPH-ephrin mediated repulsion of cells
- Dectin-2 family
- CD209 (DC-SIGN) signaling
- CD22 mediated BCR regulation
- Cyclin D associated events in G1
- Platelet Adhesion to exposed collagen
- Signaling by Erythropoietin
- Signaling by Erythropoietin
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
- Erythropoietin activates Phospholipase C gamma (PLCG)
- Erythropoietin activates STAT5
- Erythropoietin activates RAS
- Erythropoietin activates RAS
- Regulation of signaling by CBL
- Regulation of signaling by CBL
- FCGR3A-mediated IL10 synthesis
- FCGR3A-mediated phagocytosis
- Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
- Signaling by CSF3 (G-CSF)
- Signaling by CSF3 (G-CSF)
- Signaling by CSF1 (M-CSF) in myeloid cells
- Inactivation of CSF3 (G-CSF) signaling
- Inactivation of CSF3 (G-CSF) signaling
- Growth hormone receptor signaling
- Growth hormone receptor signaling
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
|
- Dasatinib
- 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
- Bosutinib
- Ponatinib
- Nintedanib
- Fostamatinib
|
|
|
MFF
|
mitochondrial fission factor |
|
|
|
|
MGLL
|
monoglyceride lipase |
- Acyl chain remodeling of DAG and TAG
- Triglyceride catabolism
- Arachidonate production from DAG
- MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
|
|
|
|
NCR1
|
natural cytotoxicity triggering receptor 1 |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
|
|
|
|
NCR3
|
natural cytotoxicity triggering receptor 3 |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
|
|
|
|
NRM
|
nurim |
|
|
|
|
ORMDL2
|
ORMDL sphingolipid biosynthesis regulator 2 |
- Sphingolipid de novo biosynthesis
|
|
|
|
PDZK1IP1
|
PDZK1 interacting protein 1 |
|
|
|
|
PEMT
|
phosphatidylethanolamine N-methyltransferase |
|
|
|
|
PEX16
|
peroxisomal biogenesis factor 16 |
- Class I peroxisomal membrane protein import
- Class I peroxisomal membrane protein import
|
|
- Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
|
|
PLCG2
|
phospholipase C gamma 2 |
- GPVI-mediated activation cascade
- Toll Like Receptor 4 (TLR4) Cascade
- Synthesis of IP3 and IP4 in the cytosol
- Generation of second messenger molecules
- Role of phospholipids in phagocytosis
- DAP12 signaling
- FCERI mediated MAPK activation
- FCERI mediated Ca+2 mobilization
- FCERI mediated Ca+2 mobilization
- CLEC7A (Dectin-1) signaling
- CLEC7A (Dectin-1) signaling
- Dectin-2 family
- Dectin-2 family
- Erythropoietin activates Phospholipase C gamma (PLCG)
- FCGR3A-mediated IL10 synthesis
- Potential therapeutics for SARS
- Signaling by CSF1 (M-CSF) in myeloid cells
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
- Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
|
|
|
|
PLP2
|
proteolipid protein 2 |
|
|
|
|
RUSF1
|
RUS family member 1 |
|
|
|
|
SEC22B
|
SEC22 homolog B, vesicle trafficking protein |
- ER-Phagosome pathway
- COPII-mediated vesicle transport
- Cargo concentration in the ER
- COPI-dependent Golgi-to-ER retrograde traffic
|
|
|
|
SFXN1
|
sideroflexin 1 |
|
|
|
|
SFXN3
|
sideroflexin 3 |
|
|
|
|
SLC10A1
|
solute carrier family 10 member 1 |
- Recycling of bile acids and salts
|
|
|
|
SLC13A4
|
solute carrier family 13 member 4 |
- Sodium-coupled sulphate, di- and tri-carboxylate transporters
|
|
|
|
SLC18A1
|
solute carrier family 18 member A1 |
|
- Reserpine
- Norepinephrine
- Ephedra sinica root
- MMDA
- Metamfetamine
|
|