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MGAT5B
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alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B |
- DAG1 core M2 glycosylations
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NOXA1
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NADPH oxidase activator 1 |
- RHO GTPases Activate NADPH Oxidases
- RAC1 GTPase cycle
- RAC3 GTPase cycle
- WNT5:FZD7-mediated leishmania damping
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NPAS2
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neuronal PAS domain protein 2 |
- BMAL1:CLOCK,NPAS2 activates circadian expression
- PPARA activates gene expression
- Heme signaling
- Expression of BMAL (ARNTL), CLOCK, and NPAS2
- Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
- The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex
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NUTF2
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nuclear transport factor 2 |
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OTX1
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orthodenticle homeobox 1 |
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PLAC8
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placenta associated 8 |
- Neutrophil degranulation
- Formation of the nephric duct
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PLEKHB2
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pleckstrin homology domain containing B2 |
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PPP2CA
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protein phosphatase 2 catalytic subunit alpha |
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Spry regulation of FGF signaling
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- PP2A-mediated dephosphorylation of key metabolic factors
- DARPP-32 events
- Degradation of beta-catenin by the destruction complex
- Beta-catenin phosphorylation cascade
- ERK/MAPK targets
- ERKs are inactivated
- MASTL Facilitates Mitotic Progression
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Initiation of Nuclear Envelope (NE) Reformation
- Co-stimulation by CD28
- Co-inhibition by CTLA4
- Platelet sensitization by LDL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Signaling by GSK3beta mutants
- CTNNB1 S33 mutants aren't phosphorylated
- CTNNB1 S37 mutants aren't phosphorylated
- CTNNB1 S45 mutants aren't phosphorylated
- CTNNB1 T41 mutants aren't phosphorylated
- APC truncation mutants have impaired AXIN binding
- AXIN missense mutants destabilize the destruction complex
- Truncations of AMER1 destabilize the destruction complex
- RHO GTPases Activate Formins
- RAF activation
- Negative regulation of MAPK pathway
- Regulation of TP53 Degradation
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- Mitotic Prometaphase
- Cyclin D associated events in G1
- Cyclin A/B1/B2 associated events during G2/M transition
- Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
- EML4 and NUDC in mitotic spindle formation
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
- PKR-mediated signaling
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
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- Vitamin E
- 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid
- (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid
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PRSS53
|
serine protease 53 |
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PSMB8
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proteasome 20S subunit beta 8 |
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Interferon alpha/beta signaling
- Proteasome assembly
- Proteasome assembly
- Antigen processing: Ub, ATP-independent proteasomal degradation
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RBPMS
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RNA binding protein, mRNA processing factor |
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RHOXF2
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Rhox homeobox family member 2 |
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SHC3
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SHC adaptor protein 3 |
- Signalling to RAS
- Signalling to RAS
- RAF/MAP kinase cascade
- RET signaling
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SPAG8
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sperm associated antigen 8 |
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SPMIP9
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sperm microtubule inner protein 9 |
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TENT5B
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terminal nucleotidyltransferase 5B |
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TEP1
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telomerase associated protein 1 |
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TFG
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trafficking from ER to golgi regulator |
- COPII-mediated vesicle transport
- Signaling by ALK fusions and activated point mutants
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- Thyroid cancer
- Non-small cell lung cancer
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TLE5
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TLE family member 5, transcriptional modulator |
- Repression of WNT target genes
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TP53BP1
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tumor protein p53 binding protein 1 |
- SUMOylation of transcription factors
- Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
- Nonhomologous End-Joining (NHEJ)
- Processing of DNA double-strand break ends
- G2/M DNA damage checkpoint
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