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HDAC4
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histone deacetylase 4 |
- NOTCH1 Intracellular Domain Regulates Transcription
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Notch-HLH transcription pathway
- SUMOylation of intracellular receptors
- SUMOylation of chromatin organization proteins
- RUNX2 regulates chondrocyte maturation
- RUNX3 regulates p14-ARF
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- Valproic acid
- Decitabine
- Zinc
- Vorinostat
- Belinostat
- Romidepsin
- Romidepsin
- Panobinostat
- Phenylbutyric acid
- N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide
- 2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL
- Entinostat
- Abexinostat
- Givinostat
- Pyroxamide
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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- Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome
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IMPA2
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inositol monophosphatase 2 |
- Synthesis of IP2, IP, and Ins in the cytosol
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- Lithium cation
- Lithium citrate
- Lithium succinate
- Lithium carbonate
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ITFG1
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integrin alpha FG-GAP repeat containing 1 |
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LTA
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lymphotoxin alpha |
- TNFR2 non-canonical NF-kB pathway
- TNFs bind their physiological receptors
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
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MBTPS1
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membrane bound transcription factor peptidase, site 1 |
- Regulation of cholesterol biosynthesis by SREBP (SREBF)
- ATF6 (ATF6-alpha) activates chaperones
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- ATF6B (ATF6-beta) activates chaperones
- CREB3 factors activate genes
- CREB3 factors activate genes
- Post-translational protein phosphorylation
- Assembly of active LPL and LIPC lipase complexes
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NDUFS2
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NADH:ubiquinone oxidoreductase core subunit S2 |
- Respiratory electron transport
- Complex I biogenesis
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- Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
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NRIP1
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nuclear receptor interacting protein 1 |
- SUMOylation of transcription cofactors
- Estrogen-dependent gene expression
- NR1H2 & NR1H3 regulate gene expression linked to lipogenesis
- NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis
- Heme signaling
- Expression of BMAL (ARNTL), CLOCK, and NPAS2
- RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
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- 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE
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RAD21
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RAD21 cohesin complex component |
- Meiotic synapsis
- Separation of Sister Chromatids
- Establishment of Sister Chromatid Cohesion
- Cohesin Loading onto Chromatin
- Resolution of Sister Chromatid Cohesion
- SUMOylation of DNA damage response and repair proteins
- Estrogen-dependent gene expression
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SERPINA4
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serpin family A member 4 |
- Platelet degranulation
- Developmental Lineage of Pancreatic Acinar Cells
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TNFSF13
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TNF superfamily member 13 |
- HuR (ELAVL1) binds and stabilizes mRNA
- TNFs bind their physiological receptors
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TNFSF14
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TNF superfamily member 14 |
- TNFR2 non-canonical NF-kB pathway
- TNFs bind their physiological receptors
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
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TRAF1
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TNF receptor associated factor 1 |
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
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TRAF2
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TNF receptor associated factor 2 |
- Caspase activation via Death Receptors in the presence of ligand
- Regulation by c-FLIP
- RIPK1-mediated regulated necrosis
- CASP8 activity is inhibited
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- TNFR2 non-canonical NF-kB pathway
- Regulation of necroptotic cell death
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Ub-specific processing proteases
- Dimerization of procaspase-8
- TNF signaling
- TRAF6 mediated IRF7 activation
- TRAF6 mediated NF-kB activation
- TRAF6 mediated NF-kB activation
- Defective RIPK1-mediated regulated necrosis
- Regulation of NF-kappa B signaling
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TRAF3
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TNF receptor associated factor 3 |
- TRAF3 deficiency - HSE
- TNFR2 non-canonical NF-kB pathway
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
- Ovarian tumor domain proteases
- TICAM1-dependent activation of IRF3/IRF7
- TRAF3-dependent IRF activation pathway
- Negative regulators of DDX58/IFIH1 signaling
- Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)
- SARS-CoV-1 activates/modulates innate immune responses
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
- Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
- Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation
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TRAF5
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TNF receptor associated factor 5 |
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UBQLN4
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ubiquilin 4 |
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VIM
|
vimentin |
- Caspase-mediated cleavage of cytoskeletal proteins
- Striated Muscle Contraction
- Interleukin-4 and Interleukin-13 signaling
- RHOBTB1 GTPase cycle
- Chaperone Mediated Autophagy
- Late endosomal microautophagy
- Aggrephagy
- Developmental Lineage of Mammary Gland Myoepithelial Cells
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- Artenimol
- Phenethyl Isothiocyanate
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WDR73
|
WD repeat domain 73 |
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ZBTB48
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zinc finger and BTB domain containing 48 |
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