Search Results for: PKP2

52 interactions involving PKP2 - plakophilin 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
DSP desmoplakin
  • Apoptotic cleavage of cell adhesion proteins
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • RND3 GTPase cycle
  • RND1 GTPase cycle
  • Zinc
  • Artenimol
  • Zinc acetate
  • Striate palmoplantar keratoderma
  • Skin fragility-woolly hair syndrome
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Naxos disease and Carvajal syndrome
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EXOSC8 exosome component 8
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Nuclear RNA decay
FHL3 four and a half LIM domains 3
GOLGA2 golgin A2
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • COPII-mediated vesicle transport
  • COPI-mediated anterograde transport
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
GRIPAP1 GRIP1 associated protein 1
GTF2IRD1 GTF2I repeat domain containing 1
HOOK2 hook microtubule tethering protein 2
HSPB2 heat shock protein family B (small) member 2
JUP junction plakoglobin
  • Adherens junctions interactions
  • VEGFR2 mediated vascular permeability
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • RHOA GTPase cycle
  • RHOB GTPase cycle
  • RHOC GTPase cycle
  • CDC42 GTPase cycle
  • RHOQ GTPase cycle
  • RHOH GTPase cycle
  • RHOJ GTPase cycle
  • Regulation of CDH11 function
  • Regulation of CDH11 function
  • Regulation of CDH19 Expression and Function
  • Regulation of CDH1 Function
  • Degradation of CDH1
  • Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
  • CDH11 homotypic and heterotypic interactions
  • Zinc
  • Zinc acetate
  • Naxos disease and Carvajal syndrome
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
KLC4 kinesin light chain 4
  • MHC class II antigen presentation
  • RHO GTPases activate KTN1
  • COPI-dependent Golgi-to-ER retrograde traffic
  • Kinesins
KRT18 keratin 18
  • Keratinization
  • Formation of the cornified envelope
  • Developmental Lineage of Mammary Gland Luminal Epithelial Cells
  • Developmental Lineage of Mammary Gland Alveolar Cells
KRT31 keratin 31
  • Keratinization
  • Formation of the cornified envelope
KRT5 keratin 5
  • Type I hemidesmosome assembly
  • Keratinization
  • Formation of the cornified envelope
  • Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
  • Developmental Lineage of Mammary Gland Luminal Epithelial Cells
  • Developmental Lineage of Mammary Gland Myoepithelial Cells
  • Developmental Lineage of Mammary Stem Cells
  • Zinc
  • Zinc acetate
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
  • Dowling-Degos disease
MAGOHB mago homolog B, exon junction complex subunit
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
MARK3 microtubule affinity regulating kinase 3
  • RAF activation
  • MAP2K and MAPK activation
  • Negative regulation of MAPK pathway
  • Signaling by moderate kinase activity BRAF mutants
  • Signaling by high-kinase activity BRAF mutants
  • Signaling by BRAF and RAF1 fusions
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • Signaling downstream of RAS mutants
  • Signaling by RAF1 mutants
  • Transcriptional and post-translational regulation of MITF-M expression and activity
  • Fostamatinib
MTUS2 microtubule associated scaffold protein 2
NCKIPSD NCK interacting protein with SH3 domain
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
NDEL1 nudE neurodevelopment protein 1 like 1
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
PIBF1 progesterone immunomodulatory binding factor 1

Page 2 out of 3 pages