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DSP |
desmoplakin |
- Apoptotic cleavage of cell adhesion proteins
- Neutrophil degranulation
- Keratinization
- Formation of the cornified envelope
- RND3 GTPase cycle
- RND1 GTPase cycle
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- Zinc
- Artenimol
- Zinc acetate
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- Striate palmoplantar keratoderma
- Skin fragility-woolly hair syndrome
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Naxos disease and Carvajal syndrome
- Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
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EIF4ENIF1 |
eukaryotic translation initiation factor 4E nuclear import factor 1 |
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EXOSC8 |
exosome component 8 |
- ATF4 activates genes in response to endoplasmic reticulum stress
- mRNA decay by 3' to 5' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
- Major pathway of rRNA processing in the nucleolus and cytosol
- Nuclear RNA decay
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FHL3 |
four and a half LIM domains 3 |
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GOLGA2 |
golgin A2 |
- Golgi Cisternae Pericentriolar Stack Reorganization
- Golgi Cisternae Pericentriolar Stack Reorganization
- COPII-mediated vesicle transport
- COPI-mediated anterograde transport
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
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GRIPAP1 |
GRIP1 associated protein 1 |
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GTF2IRD1 |
GTF2I repeat domain containing 1 |
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HOOK2 |
hook microtubule tethering protein 2 |
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HSPB2 |
heat shock protein family B (small) member 2 |
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JUP |
junction plakoglobin |
- Adherens junctions interactions
- VEGFR2 mediated vascular permeability
- Neutrophil degranulation
- Keratinization
- Formation of the cornified envelope
- RHOA GTPase cycle
- RHOB GTPase cycle
- RHOC GTPase cycle
- CDC42 GTPase cycle
- RHOQ GTPase cycle
- RHOH GTPase cycle
- RHOJ GTPase cycle
- Regulation of CDH11 function
- Regulation of CDH11 function
- Regulation of CDH19 Expression and Function
- Regulation of CDH1 Function
- Degradation of CDH1
- Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
- CDH11 homotypic and heterotypic interactions
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- Naxos disease and Carvajal syndrome
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
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KLC4 |
kinesin light chain 4 |
- MHC class II antigen presentation
- RHO GTPases activate KTN1
- COPI-dependent Golgi-to-ER retrograde traffic
- Kinesins
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KRT18 |
keratin 18 |
- Keratinization
- Formation of the cornified envelope
- Developmental Lineage of Mammary Gland Luminal Epithelial Cells
- Developmental Lineage of Mammary Gland Alveolar Cells
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KRT31 |
keratin 31 |
- Keratinization
- Formation of the cornified envelope
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KRT5 |
keratin 5 |
- Type I hemidesmosome assembly
- Keratinization
- Formation of the cornified envelope
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
- Developmental Lineage of Mammary Gland Luminal Epithelial Cells
- Developmental Lineage of Mammary Gland Myoepithelial Cells
- Developmental Lineage of Mammary Stem Cells
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- Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
- Dowling-Degos disease
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MAGOHB |
mago homolog B, exon junction complex subunit |
- Transport of Mature mRNA derived from an Intron-Containing Transcript
- mRNA Splicing - Major Pathway
- mRNA 3'-end processing
- RNA Polymerase II Transcription Termination
- Regulation of expression of SLITs and ROBOs
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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MARK3 |
microtubule affinity regulating kinase 3 |
- RAF activation
- MAP2K and MAPK activation
- Negative regulation of MAPK pathway
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF1 fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- Transcriptional and post-translational regulation of MITF-M expression and activity
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MTUS2 |
microtubule associated scaffold protein 2 |
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NCKIPSD |
NCK interacting protein with SH3 domain |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
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NDEL1 |
nudE neurodevelopment protein 1 like 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- EML4 and NUDC in mitotic spindle formation
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PIBF1 |
progesterone immunomodulatory binding factor 1 |
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