NUP62 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide
CCHCR1	coiled-coil alpha-helical rod protein 1
CENPU	centromere protein U	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
CEP57L1	centrosomal protein 57 like 1
CLIC1	chloride intracellular channel 1		Copper Artenimol
CRCT1	cysteine rich C-terminal 1
DDX3X	DEAD-box helicase 3 X-linked	Neutrophil degranulation
DGCR6	DiGeorge syndrome critical region gene 6
DPPA3	developmental pluripotency associated 3	Chromatin modifications during the maternal to zygotic transition (MZT)
DRC12	dynein regulatory complex subunit 12 homolog
DTNB	dystrobrevin beta	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
DYNLT1	dynein light chain Tctex-type 1	Neutrophil degranulation
FABP3	fatty acid binding protein 3	Triglyceride catabolism
GOPC	golgi associated PDZ and coiled-coil motif containing	RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle
GORASP2	golgi reassembly stacking protein 2	Golgi Cisternae Pericentriolar Stack Reorganization
GTF2E2	general transcription factor IIE subunit 2	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
HAUS1	HAUS augmin like complex subunit 1	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	EGFR downregulation Lysosome Vesicle Biogenesis Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell RHOU GTPase cycle Endosomal Sorting Complex Required For Transport (ESCRT) Inhibition of membrane repair Prevention of phagosomal-lysosomal fusion RHOBTB3 ATPase cycle	Citric acid
HSF2	heat shock transcription factor 2
HSF4	heat shock transcription factor 4
IDH1	isocitrate dehydrogenase (NADP(+)) 1	Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate NADPH regeneration Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import NFE2L2 regulating TCA cycle genes	Isocitric Acid Nicotinamide adenine dinucleotide phosphate Ivosidenib Olutasidenib

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