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COIL |
coilin |
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CPSF7 |
cleavage and polyadenylation specific factor 7 |
- mRNA 3'-end processing
- Processing of Capped Intron-Containing Pre-mRNA
- RNA Polymerase II Transcription Termination
- Processing of Intronless Pre-mRNAs
- RHOBTB1 GTPase cycle
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DISC1 |
DISC1 scaffold protein |
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DNAJA3 |
DnaJ heat shock protein family (Hsp40) member A3 |
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DRC4 |
dynein regulatory complex subunit 4 |
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FAM83A |
family with sequence similarity 83 member A |
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FBF1 |
Fas binding factor 1 |
- Anchoring of the basal body to the plasma membrane
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FBXO28 |
F-box protein 28 |
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FIGNL1 |
fidgetin like 1 |
- Resolution of D-loop Structures through Holliday Junction Intermediates
- Meiotic recombination
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FOSL1 |
FOS like 1, AP-1 transcription factor subunit |
- NGF-stimulated transcription
- NGF-stimulated transcription
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GLI1 |
GLI family zinc finger 1 |
- Degradation of GLI1 by the proteasome
- Degradation of GLI1 by the proteasome
- Hedgehog 'off' state
- Hedgehog 'on' state
- GLI proteins bind promoters of Hh responsive genes to promote transcription
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GOLGA2 |
golgin A2 |
- Golgi Cisternae Pericentriolar Stack Reorganization
- Golgi Cisternae Pericentriolar Stack Reorganization
- COPII-mediated vesicle transport
- COPI-mediated anterograde transport
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
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GTF2I |
general transcription factor IIi |
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HDX |
highly divergent homeobox |
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ICA1L |
islet cell autoantigen 1 like |
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IKBKG |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
- Activation of NF-kappaB in B cells
- Activation of NF-kappaB in B cells
- ER-Phagosome pathway
- NOD1/2 Signaling Pathway
- TICAM1, RIP1-mediated IKK complex recruitment
- RIP-mediated NFkB activation via ZBP1
- Downstream TCR signaling
- FCERI mediated NF-kB activation
- TAK1-dependent IKK and NF-kappa-B activation
- activated TAK1 mediates p38 MAPK activation
- JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
- SUMOylation of immune response proteins
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
- IKBKB deficiency causes SCID
- IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
- IkBA variant leads to EDA-ID
- CLEC7A (Dectin-1) signaling
- MAP3K8 (TPL2)-dependent MAPK1/3 activation
- Ub-specific processing proteases
- Ovarian tumor domain proteases
- Interleukin-1 signaling
- TRAF6 mediated NF-kB activation
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
- IRAK1 recruits IKK complex
- IKK complex recruitment mediated by RIP1
- SARS-CoV-2 activates/modulates innate and adaptive immune responses
- IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
- Regulation of NF-kappa B signaling
- PKR-mediated signaling
- SLC15A4:TASL-dependent IRF5 activation
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
- Modulation of host responses by IFN-stimulated genes
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- Incontinentia pigmenti
- Ectodermal dysplasia associated immunodeficiency (EDA-ID), including the following two diseases: NF-kappa-B essential modulator (NEMO) defect; Inhibitor of kappa-B (I-kappa-B) defect
- Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficiency (OLEDAID); Ectodermal dysplasia, anhidrotic, with immunodeficiency, osteopetrosis, and lymphedema
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ITSN1 |
intersectin 1 |
- NRAGE signals death through JNK
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- G alpha (12/13) signalling events
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- CDC42 GTPase cycle
- RHOQ GTPase cycle
- RHOG GTPase cycle
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KATNAL1 |
katanin catalytic subunit A1 like 1 |
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KDM1A |
lysine demethylase 1A |
- HDACs deacetylate histones
- HDMs demethylate histones
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Regulation of PTEN gene transcription
- Estrogen-dependent gene expression
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- Potential therapeutics for SARS
- Negative Regulation of CDH1 Gene Transcription
- Factors involved in megakaryocyte development and platelet production
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KIAA0753 |
KIAA0753 |
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