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RELA |
RELA proto-oncogene, NF-kB subunit |
- Activation of NF-kappaB in B cells
- RIP-mediated NFkB activation via ZBP1
- Regulated proteolysis of p75NTR
- Downstream TCR signaling
- NF-kB is activated and signals survival
- Senescence-Associated Secretory Phenotype (SASP)
- FCERI mediated NF-kB activation
- DEx/H-box helicases activate type I IFN and inflammatory cytokines production
- PKMTs methylate histone lysines
- Transcriptional regulation of white adipocyte differentiation
- TAK1-dependent IKK and NF-kappa-B activation
- Interleukin-1 processing
- SUMOylation of immune response proteins
- IkBA variant leads to EDA-ID
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- CD209 (DC-SIGN) signaling
- CLEC7A/inflammasome pathway
- The NLRP3 inflammasome
- Transcriptional Regulation by VENTX
- Interleukin-1 signaling
- TRAF6 mediated NF-kB activation
- Purinergic signaling in leishmaniasis infection
- SARS-CoV-1 activates/modulates innate immune responses
- Regulation of NFE2L2 gene expression
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
- Regulation of PD-L1(CD274) transcription
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- Glucosamine
- Dimethyl fumarate
- SC-236
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RFX6 |
regulatory factor X6 |
- Regulation of gene expression in beta cells
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RHOXF2 |
Rhox homeobox family member 2 |
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RIBC1 |
RIB43A domain with coiled-coils 1 |
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RIMBP3 |
RIMS binding protein 3 |
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RNF31 |
ring finger protein 31 |
- TNFR1-induced proapoptotic signaling
- Regulation of TNFR1 signaling
- TNFR1-induced NF-kappa-B signaling pathway
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RORB |
RAR related orphan receptor B |
- Nuclear Receptor transcription pathway
- Expression of BMAL (ARNTL), CLOCK, and NPAS2
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RPL18A |
ribosomal protein L18a |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Peptide chain elongation
- SRP-dependent cotranslational protein targeting to membrane
- SRP-dependent cotranslational protein targeting to membrane
- Viral mRNA Translation
- Selenocysteine synthesis
- Major pathway of rRNA processing in the nucleolus and cytosol
- Formation of a pool of free 40S subunits
- GTP hydrolysis and joining of the 60S ribosomal subunit
- Eukaryotic Translation Termination
- Regulation of expression of SLITs and ROBOs
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
- PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
- ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
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RUNX1 |
RUNX family transcription factor 1 |
- Pre-NOTCH Transcription and Translation
- SLC-mediated transport of organic cations
- RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
- RUNX1 regulates estrogen receptor mediated transcription
- Regulation of RUNX1 Expression and Activity
- Regulation of RUNX1 Expression and Activity
- RUNX1 regulates expression of components of tight junctions
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
- RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- RUNX1 regulates transcription of genes involved in BCR signaling
- RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
- RUNX1 regulates transcription of genes involved in interleukin signaling
- RUNX1 regulates transcription of genes involved in WNT signaling
- RUNX2 regulates genes involved in differentiation of myeloid cells
- RUNX3 regulates p14-ARF
- Estrogen-dependent gene expression
- Transcriptional regulation of granulopoiesis
- SARS-CoV-1 activates/modulates innate immune responses
- Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)
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- Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
- Acute myeloid leukemia (AML)
- Chronic myeloid leukemia (CML)
- Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
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RUSC1 |
RUN and SH3 domain containing 1 |
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SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
- Interconversion of polyamines
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- N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
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- Keratosis follicularis spinulosa decalvans
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SCNM1 |
sodium channel modifier 1 |
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SDCBP |
syndecan binding protein |
- Ephrin signaling
- Neurofascin interactions
- RIPK1-mediated regulated necrosis
- Regulation of necroptotic cell death
- Neutrophil degranulation
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SERTAD3 |
SERTA domain containing 3 |
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SET |
SET nuclear proto-oncogene |
- Condensation of Prophase Chromosomes
- HuR (ELAVL1) binds and stabilizes mRNA
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SF3B4 |
splicing factor 3b subunit 4 |
- mRNA Splicing - Major Pathway
- mRNA Splicing - Minor Pathway
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SH2B2 |
SH2B adaptor protein 2 |
- Regulation of KIT signaling
- Factors involved in megakaryocyte development and platelet production
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SH3GL3 |
SH3 domain containing GRB2 like 3, endophilin A3 |
- EGFR downregulation
- Negative regulation of MET activity
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- InlB-mediated entry of Listeria monocytogenes into host cell
- NGF-stimulated transcription
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SHFL |
shiftless antiviral inhibitor of ribosomal frameshifting |
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SHISA6 |
shisa family member 6 |
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