Search Results for: TRAF1

249 interactions involving TRAF1 - TNF receptor associated factor 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
TBC1D16 TBC1 domain family member 16
  • TBC/RABGAPs
TBC1D8 TBC1 domain family member 8
TBX18 T-box transcription factor 18
TCEA2 transcription elongation factor A2
TCF7L2 transcription factor 7 like 2
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • Deactivation of the beta-catenin transactivating complex
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Ca2+ pathway
  • Binding of TCF/LEF:CTNNB1 to target gene promoters
  • Repression of WNT target genes
  • Repression of WNT target genes
  • Signaling by TCF7L2 mutants
  • Transcriptional Regulation by VENTX
  • RUNX3 regulates WNT signaling
  • Formation of definitive endoderm
  • Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
  • Regulation of PD-L1(CD274) transcription
  • Type II diabetes mellitus
TCL1A TCL1 family AKT coactivator A
TEAD4 TEA domain transcription factor 4
  • YAP1- and WWTR1 (TAZ)-stimulated gene expression
  • RUNX3 regulates YAP1-mediated transcription
  • Formation of axial mesoderm
  • Zygotic genome activation (ZGA)
  • Regulation of PD-L1(CD274) transcription
TFAP2D transcription factor AP-2 delta
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Activation of the TFAP2 (AP-2) family of transcription factors
TFAP4 transcription factor AP-4
TFPT TCF3 fusion partner
  • UCH proteinases
  • DNA Damage Recognition in GG-NER
THAP7 THAP domain containing 7
TICAM1 TIR domain containing adaptor molecule 1
  • Caspase activation via Death Receptors in the presence of ligand
  • MyD88-independent TLR4 cascade
  • Toll Like Receptor 3 (TLR3) Cascade
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIP-mediated NFkB activation via ZBP1
  • TRIF-mediated programmed cell death
  • TICAM1 deficiency - HSE
  • TRAF3 deficiency - HSE
  • TLR3-mediated TICAM1-dependent programmed cell death
  • TICAM1-dependent activation of IRF3/IRF7
  • TICAM1,TRAF6-dependent induction of TAK1 complex
  • Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)
  • IKK complex recruitment mediated by RIP1
  • TRAF6-mediated induction of TAK1 complex within TLR4 complex
  • IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
  • Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7
  • Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation
TIFA TRAF interacting protein with forkhead associated domain
  • TAK1-dependent IKK and NF-kappa-B activation
  • Alpha-protein kinase 1 signaling pathway
TLE5 TLE family member 5, transcriptional modulator
  • Repression of WNT target genes
TNFAIP3 TNF alpha induced protein 3
  • NOD1/2 Signaling Pathway
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • Ovarian tumor domain proteases
  • Negative regulators of DDX58/IFIH1 signaling
TNFRSF11A TNF receptor superfamily member 11a
  • TNFR2 non-canonical NF-kB pathway
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • ENMD-1198
  • Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
  • Paget's disease of bone and related disorders, including: ; Paget's disease of bone (PDB); Familial expansile osteolysis (FEO); Early-onset Paget's disease of bone (PDB2); Expansile skeletal hyperphosphatasia (ESH); Juvenile Paget's disease (JPD)
TNFRSF12A TNF receptor superfamily member 12A
  • TNFR2 non-canonical NF-kB pathway
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
TNFRSF14 TNF receptor superfamily member 14
  • TNFs bind their physiological receptors
  • Co-inhibition by BTLA
  • Co-inhibition by BTLA
TNFRSF17 TNF receptor superfamily member 17
  • TNFs bind their physiological receptors
  • Belantamab mafodotin
  • Teclistamab
  • Idecabtagene vicleucel
  • Ciltacabtagene autoleucel
TNFRSF18 TNF receptor superfamily member 18
  • TNFs bind their physiological receptors
  • RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)

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