FAM25C and MIEF1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		FAM25C	MIEF1
Name		family with sequence similarity 25 member C	mitochondrial elongation factor 1
Structure		No pdb structure
GO Annotations	Cellular Component	None	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	None	Nucleotide Binding Protein Binding GDP Binding Identical Protein Binding ADP Binding
	Biological Process	None	Mitochondrial Fission Mitochondrion Organization Mitochondrial Fusion Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways		None	Mitochondrial ribosome-associated quality control
GWAS		Pancreas fat ( 34128465 )	Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Mean corpuscular hemoglobin ( 32888494 )
Interacting Genes		18 interacting genes: ARMC10 ARMCX3 COX16 GPD1 IGLL1 KLHL35 LCN1 LCN2 MIEF1 MIEF2 PPIC PPIF S100A6 SNX1 TDRKH TOMM20L TTPA ZFAND3	22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG
Entrez ID		644054	54471
HPRD ID		19638	13371
Ensembl ID		ENSG00000276430	ENSG00000100335
Uniprot IDs		B3EWG5	B0QY95 Q9NQG6
PDB IDs		Not available	4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
GO Terms Enriched among Interactors		Mitochondrial Outer Membrane Cyclosporin A Binding Regulation Of Mitochondrion Organization Mitochondrion Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Small Molecule Binding Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission Regulation Of Protein Targeting To Membrane Peptidyl-prolyl Cis-trans Isomerase Activity Glycerol-3-phosphate Dehydrogenase (NAD+) Activity Positive Regulation Of Hippocampal Neuron Apoptotic Process Negative Regulation Of Establishment Of Blood-brain Barrier Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity Glycerol-3-phosphate Catabolic Process Glycerol-3-phosphate Shuttle Positive Regulation Of Iron Ion Import Across Plasma Membrane Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Growth Rate TRNA Import Into Mitochondrion Cellular Response To Hydrogen Peroxide	None