TMEM179B and C1QL4

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TMEM179B	C1QL4
Name		transmembrane protein 179B	complement C1q like 4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Plasma Membrane Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane	Extracellular Region Collagen Trimer Extracellular Space
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	None	Negative Regulation Of Fat Cell Differentiation Fibroblast Proliferation Negative Regulation Of Fibroblast Proliferation ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Neutrophil degranulation	None
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )	No GWAS studies recorded
Interacting Genes		47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 SLC61A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1	19 interacting genes: CD53 CERS4 FATE1 FNDC9 GOLM1 GPR152 IL10RA LEUTX MFF RHCG SCARA5 SGTA SGTB SLC38A1 SSMEM1 TMEM179B TMPRSS2 TRHR UBQLN2
Entrez ID		374395	338761
HPRD ID		14186	17350
Ensembl ID		ENSG00000185475	ENSG00000186897
Uniprot IDs		G3V185 Q7Z7N9	A0A3B0INP7 Q86Z23
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Membrane Inorganic Anion Transport	Membrane TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of ERAD Pathway Identical Protein Binding Regulation Of ERAD Pathway Establishment Of Protein Localization To Organelle Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Interleukin-10 Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Thyrotropin-releasing Hormone Receptor Activity Ferritin Receptor Activity Protein Targeting