KIF14

Name	kinesin family member 14
Structure	No pdb structure
Interactors	3 interactors: CLK1 TUBG1 TUBGCP2
GO Annotations	Cellular Component	Nucleus Cytoplasm Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Plasma Membrane Membrane Midbody Spindle Midzone Flemming Body
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Tubulin Binding ATP Hydrolysis Activity Protein Kinase Binding PDZ Domain Binding
	Biological Process	Regulation Of Cell Growth Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Chromosome Alignment Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Cerebellar Granular Layer Structural Organization Cerebellar Purkinje Cell Layer Structural Organization Cerebellar Cortex Development Hippocampus Development Olfactory Bulb Development Cell Proliferation In Forebrain Cerebral Cortex Development Regulation Of Cell Adhesion Regulation Of Cell Migration SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Myelination Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Regulation Of Rap Protein Signal Transduction Negative Regulation Of Integrin Activation Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Establishment Of Protein Localization Cell Division Regulation Of Cell Maturation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways	RHO GTPases activate CIT RND2 GTPase cycle RND1 GTPase cycle
GWAS	Femur bone mineral density x serum urate levels interaction ( 34046847 ) Neurofibrillary tangles ( 31497858 ) Refractive error ( 32231278 ) Tandem gait ( 26219847 )
Entrez ID	9928
HPRD ID	06605
Ensembl ID	ENSG00000118193
Uniprot IDs	A0A384P5W4 Q15058
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Gamma-tubulin Complex Microtubule Nucleation Cytoplasmic Microtubule Organization Cytoplasmic Microtubule Mitotic Cell Cycle Spindle Organization Microtubule Nucleator Activity Polar Microtubule Ciliary Basal Body Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Organization Supramolecular Fiber Organization Microtubule Minus-end Binding Mitotic Spindle Microtubule Meiotic Spindle Organization Centrosome Pericentriolar Material Protein Serine/threonine/tyrosine Kinase Activity Non-motile Cilium Mitotic Sister Chromatid Segregation Microtubule-based Process Gamma-tubulin Binding Non-membrane Spanning Protein Tyrosine Kinase Activity Spindle Microtubule Sister Chromatid Segregation Condensed Nuclear Chromosome Nuclear Chromosome Segregation Cytoskeleton Organization Cell Leading Edge Apical Part Of Cell Structural Constituent Of Cytoskeleton Reproductive Process Mitotic Spindle Organization Microtubule Organizing Center Spindle Assembly