SV2A

Name	synaptic vesicle glycoprotein 2A
Structure
Novel Interactors	1 novel interactors: VPS45
Interactors	4 interactors: ATXN1 DNAJC5 LAMA5 LTB4R2
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell-cell Junction Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuromuscular Junction Cell Projection Neuron Projection Synapse Presynaptic Active Zone Presynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Kinase Binding Transmembrane Transporter Activity
	Biological Process	Neurotransmitter Transport Intracellular Calcium Ion Homeostasis Chemical Synaptic Transmission Synaptic Vesicle Priming Transmembrane Transport
Pathways	Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type A (botA) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type E (botE)
Drugs	Levetiracetam Brivaracetam Seletracetam
GWAS	Anthropometric traits ( 30166351 ) Anthropometric traits (multi-trait analysis) ( 30166351 ) Height ( 18391951 25429064 31562340 ) Hip circumference adjusted for BMI ( 34021172 ) Lung function (FEV1) ( 26635082 )
Entrez ID	9900
HPRD ID	08922
Ensembl ID	ENSG00000159164
Uniprot IDs	B4E000 Q7L0J3
PDB IDs	4V11 8JLC 8JLE 8JLF 8JLG 8JLH 8JLI 8JS8 8JS9 8K77 8UO9 8UOA 8YF0 8YF1
GO Terms Enriched among Interactors ?	Extracellular Matrix Of Synaptic Cleft Laminin-5 Complex Laminin-11 Complex Ameboidal-type Cell Migration Laminin-10 Complex Neuromuscular Junction Synaptic Vesicle Leukotriene B4 Receptor Activity Leukotriene Receptor Activity POZ Domain Binding Leukotriene Signaling Pathway Trunk Neural Crest Cell Migration Morphogenesis Of A Polarized Epithelium Keratinocyte Migration Poly(G) Binding ATP-dependent Protein Binding Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Chromaffin Granule Membrane Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Branching Involved In Salivary Gland Morphogenesis Cell Adhesion Mediator Activity Nuclear Inclusion Body Negative Regulation Of Adenylate Cyclase Activity