FARP2

Name	FERM, ARH/RhoGEF and pleckstrin domain protein 2
Structure	No pdb structure
Interactors	9 interactors: BGLT3 CDH1 CDK4 CDK6 PDZK1 SRC UBC UBE2G2 YWHAG
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Cytoskeletal Protein Binding
	Biological Process	Cell Adhesion Signal Transduction Neuron Remodeling Rac Protein Signal Transduction Hair Cycle Process Actin Cytoskeleton Organization Osteoclast Differentiation Regulation Of Integrin Activation Cell Development Semaphorin-plexin Signaling Pathway Podosome Assembly
Pathways	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion RAC1 GTPase cycle
GWAS	Body size at age 10 ( 32376654 ) Cerebrospinal fluid immune biomarker levels ( 32066700 ) Chronic lymphocytic leukemia ( 23770605 28165464 ) Copper levels ( 26025379 ) Disability (impaired activities of daily living) ( 31707593 ) Eosinophil count ( 27863252 32888494 ) Eosinophil percentage of granulocytes ( 27863252 ) Eosinophil percentage of white cells ( 32888494 27863252 ) Fibrinogen ( 23969696 ) Fibrinogen levels ( 28107422 ) Neutrophil percentage of granulocytes ( 27863252 ) Prostate cancer ( 23535732 ) Sum eosinophil basophil counts ( 27863252 ) Systolic blood pressure ( 30224653 ) Triglyceride levels ( 32154731 32203549 ) Type 1 diabetes ( 34127860 ) Vitiligo ( 27723757 )
Entrez ID	9855
HPRD ID	16885
Ensembl ID	ENSG00000006607
Uniprot IDs	O94887
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Regulation Of Cellular Localization Regulation Of Protein Localization Cyclin Binding Cyclin-dependent Protein Serine/threonine Kinase Activity Modification-dependent Protein Catabolic Process Regulation Of Cell Adhesion Regulation Of Intracellular Transport Negative Regulation Of Cell Adhesion Positive Regulation Of Fibroblast Proliferation Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin D2-CDK6 Complex Post-translational Protein Modification Negative Regulation Of TORC1 Signaling Proteolysis Involved In Protein Catabolic Process Positive Regulation Of TORC1 Signaling TORC1 Signaling Cellular Response To Oxygen-containing Compound Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Fibroblast Proliferation Cyclin D1-CDK4 Complex Cyclin D3-CDK4 Complex Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Negative Regulation Of TOR Signaling TOR Signaling Positive Regulation Of TOR Signaling Positive Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of Protein Localization Regulation Of G2/M Transition Of Mitotic Cell Cycle Macromolecule Catabolic Process Cyclin D2-CDK4 Complex Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Proteasomal Protein Catabolic Process Protein Kinase C Inhibitor Activity Regulation Of Establishment Of Protein Localization Extracellular Exosome Regulation Of Cell-cell Adhesion Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Regulation Of Cell Cycle G2/M Phase Transition Protein Kinase Activity Regulation Of Cell-matrix Adhesion Epithelial Cell Development Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Scavenger Receptor Binding Cellular Response To Progesterone Stimulus