FARP2 and BGLT3

Number of citations of the paper that reports this interaction (PubMedID 33543443)
0

Data Source:
BioGRID (unspecified method)

		FARP2	BGLT3
Description		FERM, ARH/RhoGEF and pleckstrin domain protein 2	beta globin locus transcript 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Cytoskeletal Protein Binding
	Biological Process	Cell Adhesion Signal Transduction Neuron Remodeling Rac Protein Signal Transduction Hair Cycle Process Actin Cytoskeleton Organization Osteoclast Differentiation Regulation Of Integrin Activation Cell Development Semaphorin-plexin Signaling Pathway Podosome Assembly
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion RAC1 GTPase cycle
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Cerebrospinal fluid immune biomarker levels ( 32066700) Chronic lymphocytic leukemia ( 23770605 28165464) Copper levels ( 26025379) Disability (impaired activities of daily living) ( 31707593) Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 23535732) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 30224653) Triglyceride levels ( 32154731 32203549) Type 1 diabetes ( 34127860) Vitiligo ( 27723757)	Malaria ( 31844061)
Interacting Genes		9 interacting genes: BGLT3 CDH1 CDK4 CDK6 PDZK1 SRC UBC UBE2G2 YWHAG	7 interacting genes: BARD1 FARP2 KAT7 OTUD3 PARP1 PTEN TBL2
Entrez ID		9855	103344929
HPRD ID		16885
Ensembl ID		ENSG00000006607	ENSG00000260629
Uniprot IDs		O94887
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Protein Localization Cyclin Binding Cyclin-dependent Protein Serine/threonine Kinase Activity Modification-dependent Protein Catabolic Process Regulation Of Cell Adhesion Regulation Of Intracellular Transport Negative Regulation Of Cell Adhesion Positive Regulation Of Fibroblast Proliferation Cyclin-dependent Protein Kinase Holoenzyme Complex Cyclin D2-CDK6 Complex Post-translational Protein Modification Negative Regulation Of TORC1 Signaling Proteolysis Involved In Protein Catabolic Process Positive Regulation Of TORC1 Signaling TORC1 Signaling Cellular Response To Oxygen-containing Compound Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Fibroblast Proliferation Cyclin D1-CDK4 Complex Cyclin D3-CDK4 Complex Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Negative Regulation Of TOR Signaling TOR Signaling Positive Regulation Of TOR Signaling Positive Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of Protein Localization Regulation Of G2/M Transition Of Mitotic Cell Cycle Macromolecule Catabolic Process Cyclin D2-CDK4 Complex Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Proteasomal Protein Catabolic Process Protein Kinase C Inhibitor Activity Regulation Of Establishment Of Protein Localization Extracellular Exosome Regulation Of Cell-cell Adhesion Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Regulation Of Cell Cycle G2/M Phase Transition Protein Kinase Activity Regulation Of Cell-matrix Adhesion Epithelial Cell Development Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Scavenger Receptor Binding Cellular Response To Progesterone Stimulus	Protein Modification Process NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity Site Of DNA Damage NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription, Elongation Leukocyte Differentiation NAD+-protein-histidine ADP-ribosyltransferase Activity NAD+-protein-tyrosine ADP-ribosyltransferase Activity Intracellular Signal Transduction Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Histone H3K23 Acetyltransferase Activity Histone H3K4 Acetyltransferase Activity Regulation Of DNA Metabolic Process Positive Regulation Of Myofibroblast Differentiation NAD+-protein-serine ADP-ribosyltransferase Activity Regulation Of DNA-templated Transcription Elongation Positive Regulation Of Protein Localization To Nucleus Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Histone H3-K14 Acetyltransferase Complex Response To Dithiothreitol DNA Repair Regulation Of Phosphorus Metabolic Process DNA ADP-ribosylation Negative Regulation Of ATP Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Stress NAD DNA ADP-ribosyltransferase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission DNA Replication-dependent Chromatin Disassembly Protein K6-linked Deubiquitination Regulation Of Base-excision Repair Myeloid Leukocyte Differentiation ATP Generation From Poly-ADP-D-ribose Response To Ionizing Radiation Signal Transduction BRCA1-B Complex Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Response To Anisomycin Response To Sorbitol
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