CASP5

Name	caspase 5
Structure	No pdb structure
Interactors	3 interactors: MAX NLRP1 PPHLN1
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex NLRP1 Inflammasome Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Apoptotic Process Substantia Nigra Development Interleukin-18-mediated Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Inflammatory Response Protein Maturation Cellular Response To Mechanical Stimulus
Pathways	Pyroptosis CASP5 inflammasome assembly CASP5-mediated substrate cleavage
GWAS	No GWAS studies recorded
Entrez ID	838
HPRD ID	04048
Ensembl ID	ENSG00000137757
Uniprot IDs	P51878
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Myc-Max Complex Mad-Max Complex Protein Localization To Heterochromatin Positive Regulation Of Pyroptotic Inflammatory Response Self Proteolysis NLRP3 Inflammasome Complex NLRP1 Inflammasome Complex Cysteine-type Endopeptidase Activator Activity NLRP1 Inflammasome Complex Assembly Cellular Response To UV-B Canonical Inflammasome Complex Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Pyroptotic Cell Death