SLC4A3

Name	solute carrier family 4 member 3
Structure
Interactors	6 interactors: ANK1 CA2 CA4 DRD2 PRKCE UBASH3A
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Solute:inorganic Anion Antiporter Activity Protein Binding Monoatomic Anion Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity Chloride:bicarbonate Antiporter Activity
	Biological Process	Monoatomic Ion Transport Monoatomic Anion Transport Inorganic Anion Transport Bicarbonate Transport PH Reduction Regulation Of Intracellular PH Transmembrane Transport Cardiac Conduction Cardiac Muscle Cell Action Potential Monoatomic Anion Transmembrane Transport Regulation Of Cardiac Muscle Cell Action Potential Transport Across Blood-brain Barrier Chloride Transmembrane Transport
Pathways	Bicarbonate transporters
GWAS	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Height ( 33713608 ) Immune response to measles-mumps-rubella vaccine ( 24811271 ) QT interval ( 29874175 )
Entrez ID	6508
HPRD ID	00109
Ensembl ID	ENSG00000114923
Uniprot IDs	P48751
PDB IDs	8Y85 8Y86 8Y8K 8ZLE
GO Terms Enriched among Interactors ?	Regulation Of Synaptic Transmission, GABAergic Secretion Positive Regulation Of Synaptic Transmission Carbonate Dehydratase Activity Positive Regulation Of Synaptic Transmission, GABAergic Cellular Response To Ethanol Response To Morphine Positive Regulation Of Cytokinesis Cell Periphery Positive Regulation Of Dipeptide Transmembrane Transport Regulation Of Monoatomic Ion Transport Cyanamide Hydratase Activity Modulation Of Chemical Synaptic Transmission Response To Alkaloid Positive Regulation Of Cell Division Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Response To Ethanol G Protein-coupled Receptor Complex Regulation Of Sodium Ion Transport Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Regulation Of Cytokinesis Ethanol Binding Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Negative Regulation Of Dopamine Receptor Signaling Pathway TRAM-dependent Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Hormone Secretion Lyase Activity Regulation Of Insulin Secretion Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Renal Sodium Excretion Negative Regulation Of Dopamine Secretion Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Toxin Catabolic Process Arylesterase Activity Positive Regulation Of Cellular PH Reduction Positive Regulation Of Transport Regulation Of Chloride Transport Regulation Of Peptide Hormone Secretion Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Dephosphorylation Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression