COPS7B

Name	COP9 signalosome subunit 7B
Structure
Interactors	6 interactors: APP BEX5 EIF3E NMI PMF1 UBC
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol COP9 Signalosome Protein-containing Complex
	Molecular Function	Protein Binding
	Biological Process	Protein Deneddylation COP9 Signalosome Assembly Regulation Of Protein Neddylation
Pathways	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
GWAS	Height ( 18391951 )
Entrez ID	64708
HPRD ID	09889
Ensembl ID	ENSG00000144524
Uniprot IDs	A0A087X1P5 J3KQ34 J3KQ41 Q6ZTQ7 Q9H9Q2
PDB IDs	6R6H 6R7F 6R7H 6R7I 6R7N 8H38 8H3A 8H3F
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Macrophage Activation Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Myeloid Leukocyte Activation Growth Factor Receptor Binding Main Axon Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Eukaryotic Translation Initiation Factor 3 Complex, EIF3e Negative Regulation Of Interferon-alpha Production Positive Regulation Of Protein K48-linked Ubiquitination MIS12/MIND Type Complex Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Protein Metabolic Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Protein K48-linked Ubiquitination Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion