TFB2M

Name	transcription factor B2, mitochondrial
Structure
Novel Interactors	1 novel interactors: MUC1
Interactors	3 interactors: PNP POLRMT TFAM
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity RNA Binding Methyltransferase Activity RRNA (adenine-N6-)-methyltransferase Activity Transferase Activity Mitochondrial Transcription Factor Activity
	Biological Process	RRNA Modification RRNA Processing Mitochondrial Transcription Transcription Initiation At Mitochondrial Promoter RRNA Methylation Methylation
Pathways	Mitochondrial transcription initiation Transcriptional activation of mitochondrial biogenesis
GWAS	Bipolar disorder ( 31043756 ) hemolysis of donated blood (osmotic) ( 34014839 ) Metabolite levels ( 23823483 )
Entrez ID	64216
HPRD ID	09520
Ensembl ID	ENSG00000162851
Uniprot IDs	Q9H5Q4
PDB IDs	6ERO 6ERP 6ERQ
GO Terms Enriched among Interactors ?	Mitochondrial Promoter Sequence-specific DNA Binding Transcription Initiation At Mitochondrial Promoter Mitochondrial Transcription Mitochondrial Nucleoid Mitochondrial RNA Metabolic Process DNA-templated Transcription Initiation Purine-nucleoside Phosphorylase Activity Purine Nucleobase Binding Urate Biosynthetic Process Nicotinamide Riboside Catabolic Process Guanosine Phosphorylase Activity Inosine Catabolic Process Deoxyinosine Catabolic Process Mitochondrial DNA-directed RNA Polymerase Complex Nucleobase-containing Compound Biosynthetic Process Nucleoside Binding Deoxyadenosine Catabolic Process DAMP Catabolic Process Mitochondrial Transcription Factor Activity Purine Ribonucleoside Catabolic Process Purine Deoxyribonucleoside Metabolic Process IMP Catabolic Process Deoxyribonucleoside Catabolic Process Pentosyltransferase Activity Purine Ribonucleoside Salvage Purine Nucleoside Catabolic Process 5'-3' RNA Polymerase Activity Allantoin Metabolic Process Urate Metabolic Process Negative Regulation Of Cell Adhesion Mediated By Integrin Phosphate Ion Binding Nucleoside Salvage Purine Nucleoside Monophosphate Catabolic Process Mitochondrial DNA Replication Negative Regulation Of Transcription By Competitive Promoter Binding Nucleobase-containing Small Molecule Catabolic Process Deoxyribonucleoside Monophosphate Catabolic Process Mitochondrial Matrix Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic G1 DNA Damage Checkpoint Signaling DNA-templated Transcription Mitotic G1/S Transition Checkpoint Signaling IMP Metabolic Process Sequence-specific DNA Binding Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitochondrial DNA Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Purine Nucleoside Metabolic Process Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process