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PI4KB

Name phosphatidylinositol 4-kinase beta
Structure PDB 2N73
Interactors 5 interactors: MYCBP2 NCS1 YWHAB YWHAG YWHAQ
GO Annotations Cellular Component
  • Golgi Membrane
  • Cytoplasm
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Endosome
  • Endoplasmic Reticulum
  • Golgi Apparatus
  • Cytosol
  • Endomembrane System
  • Membrane
  • Rough Endoplasmic Reticulum Membrane
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Nucleotide Binding
  • 1-phosphatidylinositol 4-kinase Activity
  • Protein Binding
  • ATP Binding
  • Kinase Activity
  • Transferase Activity
  • 14-3-3 Protein Binding
Biological Process
  • Lipid Metabolic Process
  • Phosphatidylinositol Biosynthetic Process
  • Receptor-mediated Endocytosis
  • Lysosome Organization
  • Signal Transduction
  • Phosphatidylinositol Phosphate Biosynthetic Process
  • Phosphatidylinositol-mediated Signaling
  • Inner Ear Development
Pathways
  • Synthesis of PIPs at the Golgi membrane
Drugs
  • Fostamatinib
GWAS
  • Body mass index ( 26426971 )
  • Gut microbiota (functional units) ( 27694959 )
Entrez ID 5298
HPRD ID 11805
Ensembl ID ENSG00000143393
Uniprot IDs A0A0B4J1S8 Q9UBF8
PDB IDs 2N73 4D0L 4D0M 4WAE 4WAG 5C46 5C4G 5EUQ 5FBL 5FBQ 5FBR 5FBV 5FBW 5LX2 5NAS 6GL3 8Q6F 8Q6G 8Q6H 8VOF
GO Terms Enriched among Interactors ?
  • Protein Domain Specific Binding
  • Protein Targeting
  • Protein Sequestering Activity
  • Focal Adhesion
  • Identical Protein Binding
  • Protein Kinase C Inhibitor Activity

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