PGGT1B

Name	protein geranylgeranyltransferase type I subunit beta
Structure	No pdb structure
Interactors	6 interactors: CDC42 FNTA GNG2 KRAS RHOB RRAS2
GO Annotations	Cellular Component	CAAX-protein Geranylgeranyltransferase Complex
	Molecular Function	Catalytic Activity Prenyltransferase Activity Protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Protein Prenyltransferase Activity Transferase Activity Metal Ion Binding
	Biological Process	Protein Geranylgeranylation
Drugs	L-778123 Geranylgeranyl diphosphate 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE
GWAS	Longevity ( 30294719 )
Entrez ID	5229
HPRD ID	03612
Ensembl ID	ENSG00000164219
Uniprot IDs	P53609
PDB IDs	Not available
GO Terms Enriched among Interactors ?	GDP Binding GTPase Activity Small GTPase-mediated Signal Transduction GTP Binding Focal Adhesion Positive Regulation Of Rac Protein Signal Transduction Regulation Of Rac Protein Signal Transduction Intracellular Signaling Cassette Signal Transduction G Protein Activity Positive Regulation Of Small GTPase Mediated Signal Transduction Plasma Membrane Peptide Pheromone Maturation Ras Protein Signal Transduction Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility GBD Domain Binding Storage Vacuole CAAX-protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Complex Protein Farnesyltransferase Activity Protein Farnesyltransferase Complex Positive Regulation Of Locomotion Endothelin Receptor Signaling Pathway Involved In Heart Process Golgi Membrane Protein Farnesylation GMP Binding Forebrain Astrocyte Development Positive Regulation Of Schwann Cell Migration Schwann Cell Migration Nucleotide Binding Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Rab Geranylgeranyltransferase Activity Protein Geranylgeranyltransferase Activity Response To Isolation Stress Intracellular Signal Transduction Protein Prenyltransferase Activity Protein Geranylgeranylation LRR Domain Binding Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Response To Gravity Extracellular Exosome Regulation Of Cell Migration Actin Filament Organization Leading Edge Membrane Thioesterase Binding