CD244

Name	CD244 molecule
Structure	No pdb structure
Novel Interactors	6 novel interactors: ACO2 OLFML2B PCGF1 PDGFRA SH2D1A TOMM40L
Interactors	5 interactors: ARHGEF7 CD247 CD48 LAT SH2D1B
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Membrane Raft
	Molecular Function	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding
	Biological Process	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Immune System Process Immune Response Signal Transduction Natural Killer Cell Activation Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production
Pathways	Cell surface interactions at the vascular wall
GWAS	Crohn's disease ( 21102463 ) Inflammatory bowel disease ( 23128233 ) Lymphocyte percentage of white cells ( 32888494 ) Neutrophil percentage of white cells ( 32888494 ) White blood cell count ( 32888494 )
Entrez ID	51744
HPRD ID	16121
Ensembl ID	ENSG00000122223
Uniprot IDs	Q9BZW8
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Cell Activation Leukocyte Activation Adaptive Immune Response Lymphocyte Activation Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Immune Response Immune Response Natural Killer Cell Activation Regulation Of Natural Killer Cell Mediated Immunity Platelet-derived Growth Factor Alpha-receptor Activity Negative Regulation Of Microtubule Nucleation Aconitate Hydratase Activity Fc-gamma Receptor III Complex Gamma-delta T Cell Receptor Complex Immune Effector Process Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Phospholipase C Activator Activity Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Metanephric Glomerular Capillary Formation Platelet-derived Growth Factor Receptor-ligand Complex TCR Signalosome