CHMP1A

Name	charged multivesicular body protein 1A
Structure
Interactors	18 interactors: C14orf119 CHMP1B DDIT4L GORASP2 LNPK MITD1 NR1I2 PSMA1 SDCBP STAMBP TXN2 UBE2I USP8 VPS4A VPS4B VTA1 YES1 ZDHHC17
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore Condensed Nuclear Chromosome ESCRT III Complex Nucleus Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Early Endosome Multivesicular Body Microtubule Organizing Center Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Nuclear Matrix Midbody Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	Protein Binding Metallopeptidase Activity Zinc Ion Binding Protein Domain Specific Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Plasma Membrane Repair Autophagy Nucleus Organization Vacuolar Transport Mitotic Chromosome Condensation Mitotic Metaphase Chromosome Alignment Negative Regulation Of Gene Expression Regulation Of Centrosome Duplication Protein Transport Vesicle-mediated Transport Nuclear Membrane Reassembly Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Cell Division Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly
Pathways	HCMV Late Events
GWAS	Basal cell carcinoma ( 33549134 ) Brain morphology (MOSTest) ( 32665545 ) Diastolic blood pressure ( 30578418 ) Estimated glomerular filtration rate ( 31152163 ) Hemoglobin levels ( 32327693 ) Low tan response ( 29739929 ) Mean reticulocyte volume ( 32888494 ) Medication use (agents acting on the renin-angiotensin system) ( 31015401 ) Medication use (calcium channel blockers) ( 31015401 ) Medication use (diuretics) ( 31015401 ) Plasma homocysteine levels ( 30339177 ) Red vs. brown/black hair color ( 30531825 )
Entrez ID	5119
HPRD ID	01237
Ensembl ID	ENSG00000131165
Uniprot IDs	A0A6Q8PFX8 Q9HD42
PDB IDs	2JQ9 2YMB 4A5X
GO Terms Enriched among Interactors ?	ESCRT III Complex Disassembly ESCRT Complex Disassembly Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Midbody Abscission Nuclear Membrane Reassembly Viral Budding Mitotic Cytokinetic Process Endosome Organization Multivesicular Body Assembly Multivesicular Body Organization Late Endosome To Vacuole Transport Cytokinetic Process Endosome Transport Via Multivesicular Body Sorting Pathway Nuclear Membrane Organization Viral Budding From Plasma Membrane Membrane Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Midbody Late Endosome To Lysosome Transport Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Late Endosomal Microautophagy Nuclear Pore Cytoskeleton-dependent Cytokinesis Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosome Endosome Membrane Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Vesicle Organization Membrane Fission Protein-containing Complex Disassembly Viral Process Mitotic Metaphase Chromosome Alignment Late Endosome Membrane Autophagosome Maturation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Vacuolar Transport Metaphase Chromosome Alignment Mitotic Cytokinesis Mitotic Nuclear Membrane Reassembly ATPase Complex Chromosome Localization Cell Division Extracellular Exosome Positive Regulation Of Exocytosis Nucleus Organization Proteolysis