LAMB2

Name	laminin subunit beta 2
Structure	No pdb structure
Novel Interactors	1 novel interactors: CTNNB1
Interactors	12 interactors: ATXN7 CIP2A HOXA1 KPNA2 ORC5 PIK3R2 PLEKHA5 RBL1 STAT3 STIP1 TSR2 ZNF512B
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-3 Complex Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Synaptic Cleft Laminin Complex Laminin-11 Complex Synapse Extracellular Exosome Protein Complex Involved In Cell-matrix Adhesion
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding Structural Constituent Of Synapse-associated Extracellular Matrix
	Biological Process	Cell Morphogenesis Cell Adhesion Axon Guidance Neuromuscular Junction Development Visual Perception Astrocyte Development Schwann Cell Development Neuron Projection Development Positive Regulation Of Cell Adhesion Axon Extension Involved In Regeneration Synapse Organization Positive Regulation Of Muscle Cell Differentiation Retina Development In Camera-type Eye Metanephric Podocyte Development Metanephric Glomerular Basement Membrane Development Regulation Of Basement Membrane Organization Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways	Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Diseases	Pierson syndrome
GWAS	Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Mood instability ( 31168069 ) Myocardial infarction ( 33532862 ) PR interval ( 32439900 ) Resting heart rate ( 27798624 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 ) Ulcerative colitis ( 28067908 ) Waist circumference adjusted for body mass index ( 34021172 )
Entrez ID	3913
HPRD ID	01034
Ensembl ID	ENSG00000172037
Uniprot IDs	P55268
PDB IDs	Not available