GZMM

Name	granzyme M
Structure
Interactors	6 interactors: DFFA EZR NPM1 PARP1 TUBA1B ZNF774
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	T Cell Mediated Cytotoxicity Immune System Process Proteolysis Apoptotic Process Killing Of Cells Of Another Organism Innate Immune Response Protein Maturation
Pathways	Alternative complement activation
GWAS	No GWAS studies recorded
Entrez ID	3004
HPRD ID	02633
Ensembl ID	ENSG00000197540
Uniprot IDs	P51124 U3KQV5
PDB IDs	2ZGC 2ZGH 2ZGJ 2ZKS
GO Terms Enriched among Interactors ?	Macrophage Differentiation NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity Protein-DNA Complex NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity Protein-containing Complex NAD+-protein-histidine ADP-ribosyltransferase Activity Positive Regulation Of Protein Localization NAD+-protein-tyrosine ADP-ribosyltransferase Activity Regulation Of MRNA Stability Involved In Cellular Response To UV Regulation Of EIF2 Alpha Phosphorylation By DsRNA Cellular Response To UV DNA Metabolic Process DNA ADP-ribosylation Positive Regulation Of Myofibroblast Differentiation Cellular Response To Light Stimulus Regulation Of Base-excision Repair Myeloid Leukocyte Differentiation Response To UV Negative Regulation Of ATP Biosynthetic Process Cellular Response To Radiation NAD+-protein-serine ADP-ribosyltransferase Activity ATP Generation From Poly-ADP-D-ribose Negative Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Localization To Nucleus NAD DNA ADP-ribosyltransferase Activity Negative Regulation Of Phosphate Metabolic Process Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Deoxyribonuclease Activity Negative Regulation Of Apoptotic DNA Fragmentation Deoxyribonuclease Inhibitor Activity Negative Regulation Of Nuclease Activity Negative Regulation Of Catalytic Activity Regulation Of Endoribonuclease Activity Intestinal Hexose Absorption Terminal Web Assembly Protein Localization To Cell Cortex Intestinal D-glucose Absorption Transcription Pausing By RNA Polymerase II Replication Fork Reversal Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Regulation Of Ribonuclease Activity Positive Regulation Of Centrosome Duplication Membrane To Membrane Docking Regulation Of Microvillus Length Microtubule-based Process Positive Regulation Of Protein Localization To Nucleolus Ribosomal Large Subunit Export From Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process