ANKRD17

Name	ankyrin repeat domain 17
Structure	No pdb structure
Interactors	6 interactors: ADH6 APC ECPAS ITSN2 MDM2 RNF10
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Membrane
	Molecular Function	Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding
	Biological Process	Immune System Process Regulation Of DNA Replication Defense Response To Bacterium Positive Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Positive Regulation Of Cell Cycle Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of MDA-5 Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
GWAS	Apolipoprotein B levels ( 32203549 ) Cholesterol ester levels in large LDL ( 29084231 ) Cholesterol ester levels in medium LDL ( 29084231 ) Esterified cholesterol levels ( 29084231 ) Free cholesterol levels in large LDL ( 29084231 ) Hematocrit ( 32888494 ) Large LDL particle concentration ( 29084231 ) Medium LDL particle concentration ( 29084231 ) Prostate cancer ( 23535732 ) Red blood cell count ( 32888494 ) Smooth-surface caries ( 24556642 ) Total cholesterol levels in large LDL ( 29084231 ) Total cholesterol levels in medium LDL ( 29084231 ) Total cholesterol levels in small LDL ( 29084231 )
Entrez ID	26057
HPRD ID	10648
Ensembl ID	ENSG00000132466
Uniprot IDs	O75179
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Protein Catabolic Process Heart Valve Development Proteolysis Involved In Protein Catabolic Process Proteasomal Protein Catabolic Process Endocardial Cushion Morphogenesis Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Proteolysis Response To Formaldehyde Cellular Response To Vitamin B1 Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Clathrin-dependent Synaptic Vesicle Endocytosis Centrosome Response To Vitamin B1 Response To Water-immersion Restraint Stress Cellular Response To Actinomycin D Regulation Of G1/S Transition Of Mitotic Cell Cycle NEDD8 Ligase Activity Response To Actinomycin D Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To UV-C Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Catabolic Process Receptor Serine/threonine Kinase Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Localization To Centrosome Alcohol Dehydrogenase (NAD+) Activity Leading Edge Membrane Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Atrial Septum Development Fibroblast Activation Peroxisome Proliferator Activated Receptor Binding Cellular Response To Antibiotic 5S RRNA Binding Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation