ADAM2

Name	ADAM metallopeptidase domain 2
Structure	No pdb structure
Interactors	2 interactors: CD9 CLGN
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Protein-containing Complex
	Molecular Function	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity
	Biological Process	Proteolysis Cell Adhesion Binding Of Sperm To Zona Pellucida Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Visual Learning Male Gonad Development Gene Expression Positive Regulation Of Gene Expression Adult Behavior
Pathways	Interaction With Cumulus Cells And The Zona Pellucida
GWAS	Restless legs syndrome ( 29029846 )
Entrez ID	2515
HPRD ID	03322
Ensembl ID	ENSG00000104755
Uniprot IDs	B4DWY7 Q6P2G0 Q99965
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Sperm-egg Recognition Cell-cell Recognition Single Fertilization Cell Recognition Fertilization Myoblast Fusion Involved In Skeletal Muscle Regeneration Paranodal Junction Assembly Negative Regulation Of Platelet Aggregation Negative Regulation Of Homotypic Cell-cell Adhesion Myoblast Fusion Oligodendrocyte Development Plasma Membrane Fusion Cellular Response To Low-density Lipoprotein Particle Stimulus Regulation Of Platelet Aggregation Glial Cell Migration Platelet Alpha Granule Membrane Negative Regulation Of Platelet Activation Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Binding Of Sperm To Zona Pellucida Cellular Response To Lipoprotein Particle Stimulus Cell-cell Fusion Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Reproductive Process Negative Regulation Of Coagulation Regulation Of Macrophage Migration Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Regulation Of Platelet Activation Protein Folding Chaperone Receptor Internalization Clathrin-coated Endocytic Vesicle Membrane Negative Regulation Of Wound Healing Glial Cell Development Platelet Activation Regulation Of Hemostasis Regulation Of Blood Coagulation Endocytic Vesicle Membrane Extracellular Vesicle ERAD Pathway Unfolded Protein Binding Cell-cell Junction Assembly Plasma Membrane Organization Regulation Of Wound Healing Regulation Of Mononuclear Cell Migration Integrin Binding