ETHE1

Name	ETHE1 persulfide dioxygenase
Structure
Interactors	9 interactors: APP ATG9A ATP6V1H GORASP2 IGSF21 KRTAP19-2 LRIF1 RELA TXN2
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Sulfur Dioxygenase Activity Dioxygenase Activity
	Biological Process	Glutathione Metabolic Process Hydrogen Sulfide Metabolic Process
Pathways	Sulfide oxidation to sulfate
GWAS	No GWAS studies recorded
Entrez ID	23474
HPRD ID	09764
Ensembl ID	ENSG00000105755
Uniprot IDs	A0A0S2Z580 A0A0S2Z5B3 A0A0S2Z5N8 B2RCZ7 O95571
PDB IDs	4CHL
GO Terms Enriched among Interactors ?	Negative Regulation Of MiRNA Transcription Positive Regulation Of Amyloid Precursor Protein Catabolic Process Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Positive Regulation Of Interleukin-1 Production Response To Interleukin-1 Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Synaptic Membrane Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Regulation Of Interleukin-1 Production Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-6 Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Interleukin-1 Beta Production Lipoprotein Particle Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Regulation Of Interleukin-1 Beta Production NF-kappaB P50/p65 Complex Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Response To Purine-containing Compound Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Recycling Endosome Positive Regulation Of Amyloid Fibril Formation