DNAJC8

Name	DnaJ heat shock protein family (Hsp40) member C8
Structure
Interactors	9 interactors: AGTR1 APP CEBPA FBXO25 HMGA1 IKBKG RPL34 SRPK1 SRPK2
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Intercellular Bridge
	Molecular Function	Protein Binding Hsp70 Protein Binding
Pathways	mRNA Splicing - Major Pathway
GWAS	Aspartate aminotransferase levels ( 33547301 ) Hematocrit ( 32888494 )
Entrez ID	22826
HPRD ID	13236
Ensembl ID	ENSG00000126698
Uniprot IDs	O75937
PDB IDs	7VPX
GO Terms Enriched among Interactors ?	Intracellular Signal Transduction Defense Response Protein-containing Complex Organization Protein Heterodimerization Activity Intracellular Signaling Cassette Positive Regulation Of Inflammatory Response Molecular Function Activator Activity Positive Regulation Of Viral Genome Replication Positive Regulation Of Proteolysis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Response To Stress Innate Immune Response Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Positive Regulation Of Reactive Oxygen Species Metabolic Process Angiotensin Type I Receptor Activity Amyloid-beta Complex Growth Cone Lamellipodium Defense Response To Symbiont Regulation Of Response To Calcium Ion Defense Response To Other Organism Amylin Binding Positive Regulation Of Toll Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Viral Process Chromatin Organization Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Regulation Of Cell Population Proliferation Signal Transduction Regulation Of Inflammatory Response Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Positive Regulation Of Defense Response Renin-angiotensin Regulation Of Aldosterone Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development