BAZ1A

Name	bromodomain adjacent to zinc finger domain 1A
Structure
Interactors	9 interactors: MTNR1A SATB1 SMAD2 SMAD9 SMARCA5 SRPK2 SUMO2 XRCC5 XRCC6
GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Pericentric Heterochromatin CHRAC ACF Complex
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA-templated DNA Replication Regulation Of DNA Replication Nucleosome Assembly Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Heterochromatin Formation Positive Regulation Of DNA Replication
GWAS	Alanine aminotransferase levels ( 33547301 ) Aspartate aminotransferase levels ( 33547301 ) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644 ) Heel bone mineral density ( 30598549 28869591 ) High light scatter reticulocyte count ( 27863252 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 27863252 ) Hip circumference adjusted for BMI ( 34021172 ) Hip index ( 34021172 ) Immature fraction of reticulocytes ( 32888494 27863252 ) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199 ) Mean corpuscular volume ( 27863252 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Monocyte count ( 32888494 ) Non-small cell lung cancer ( 31326317 ) Red blood cell count ( 32888494 ) Response to bupropion in depression ( 27622933 ) Reticulocyte count ( 32888494 27863252 ) Reticulocyte fraction of red cells ( 32888494 27863252 )
Entrez ID	11177
HPRD ID	12034
Ensembl ID	ENSG00000198604
Uniprot IDs	Q9NRL2
PDB IDs	5UIY
GO Terms Enriched among Interactors ?	Double-stranded DNA Binding DNA End Binding Ku70:Ku80 Complex DNA-dependent Protein Kinase Complex DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity SMAD Protein Complex Nonhomologous End Joining Complex Heteromeric SMAD Protein Complex Nuclear Telomere Cap Complex Double-stranded Telomeric DNA Binding Regulation Of RNA Metabolic Process I-SMAD Binding Regulation Of Nucleobase-containing Compound Metabolic Process Helicase Activity Nucleoplasm SMAD Protein Signal Transduction Telomeric DNA Binding Cellular Response To Gamma Radiation Chromatin ATP-dependent Activity, Acting On DNA Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Helicase Activity Transcription Regulator Complex Innate Immune Response Negative Regulation Of DNA-templated Transcription Protein-DNA Complex DNA Binding Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Chromosome Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Response To Gamma Radiation Negative Regulation Of RNA Metabolic Process Defense Response To Symbiont Defense Response To Other Organism Double-strand Break Repair Via Nonhomologous End Joining Ubiquitin Protein Ligase Binding Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Damaged DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Ionizing Radiation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process