CHD1

Name	chromodomain helicase DNA binding protein 1
Structure
Novel Interactors	1 novel interactors: FER
Interactors	9 interactors: BCLAF1 H3-3A H3-4 HDAC1 NCOR1 SAFB SPP1 SRSF3 SSRP1
GO Annotations	Cellular Component	Nuclear Chromosome Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding DNA Binding Chromatin Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding Histone H3K4me3 Reader Activity ATP-dependent Chromatin Remodeler Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Nucleosome Organization Host-mediated Activation Of Viral Transcription
Pathways	Estrogen-dependent gene expression
GWAS	Basophil percentage of white cells ( 27863252 ) Eosinophil count ( 27863252 ) Eosinophil percentage of granulocytes ( 27863252 ) Eosinophil percentage of white cells ( 27863252 32888494 ) Mean reticulocyte volume ( 32888494 ) Neutrophil percentage of granulocytes ( 27863252 ) Periodontitis (Mean PAL) ( 24024966 ) Renal sinus fat ( 22044751 )
Entrez ID	1105
HPRD ID	03668
Ensembl ID	ENSG00000153922
Uniprot IDs	A0A087WVF4 B3KT33 O14646
PDB IDs	2B2T 2B2U 2B2V 2B2W 2B2Y 2N39 4B4C 4NW2 4O42 5AFW 8UMG
GO Terms Enriched among Interactors ?	Regulation Of Androgen Receptor Signaling Pathway Chromatin Organization Response To Macrophage Colony-stimulating Factor Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nucleosome Assembly DNA Binding Negative Regulation Of Androgen Receptor Signaling Pathway Nucleosome Organization RNA Polymerase II Core Promoter Sequence-specific DNA Binding Response To Platelet-derived Growth Factor Protein-DNA Complex Assembly Response To Peptide Response To Cytokine Nucleoplasm Nucleosomal DNA Binding Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone Deacetylase Complex Embryo Implantation Chromatin Remodeling Heterochromatin Constitutive Heterochromatin Formation Adherens Junction Disassembly Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Transcription Repressor Complex Regulation Of Gene Expression Regulation Of RNA Metabolic Process Nucleus Regulation Of Macromolecule Biosynthetic Process Cell-cell Junction Disassembly Structural Constituent Of Chromatin Krueppel-associated Box Domain Binding Protein-RNA Sequence-specific Adaptor Activity Positive Regulation Of Estradiol Secretion Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Cytokine Stimulus Kit Signaling Pathway Protein Lysine Delactylase Activity Fungiform Papilla Formation Cellular Response To Leukemia Inhibitory Factor Response To Leukemia Inhibitory Factor Regulation Of Estradiol Secretion Male Gonad Development Cellular Response To Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Mast Cell Activation Involved In Immune Response Tyrosine Phosphorylation Of STAT Protein Regulation Of Macromolecule Metabolic Process Extracellular Matrix-cell Signaling Chromatin Gonad Development Nucleosome