TRIM10

Name	tripartite motif containing 10
Structure
Interactors	19 interactors: CDK2 GEM HGS LNX1 PRKAB2 PSMA1 SCNM1 STING1 TRIM35 TRIM44 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 YPEL3 ZNF148 ZNF414 ZNF620
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Erythrocyte Differentiation Innate Immune Response Host-mediated Suppression Of Symbiont Invasion
Pathways	Interferon gamma signaling
GWAS	Anger ( 24489884 ) Autism spectrum disorder or schizophrenia ( 28540026 ) High light scatter reticulocyte count ( 27863252 32888494 ) High light scatter reticulocyte percentage of red cells ( 27863252 32888494 ) HIV-1 control ( 20041166 ) Immature fraction of reticulocytes ( 27863252 32888494 ) Mean corpuscular hemoglobin concentration ( 27863252 32888494 ) Mean reticulocyte volume ( 32888494 ) Neuroticism ( 29255261 ) Red cell distribution width ( 27863252 32888494 ) Reticulocyte count ( 27863252 32888494 ) Reticulocyte fraction of red cells ( 27863252 32888494 ) Tonsillitis ( 30037793 )
Entrez ID	10107
HPRD ID	05752
Ensembl ID	ENSG00000204613
Uniprot IDs	A0A1U9X8M5 Q9UDY6
PDB IDs	7QS0
GO Terms Enriched among Interactors ?	Ubiquitin Conjugating Enzyme Activity Ubiquitin Protein Ligase Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Catabolic Process Zinc Ion Binding Positive Regulation Of Defense Response To Virus By Host Macromolecule Catabolic Process Protein K11-linked Ubiquitination Regulation Of Defense Response To Virus By Host Cyclic-di-GMP Binding STING Complex Protein Modification Process Nucleus Proteolysis Nucleotide Binding Y Chromosome Positive Regulation Of Heterochromatin Formation Transferase Activity Metal Ion Binding Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Regulation Of Defense Response To Virus Positive Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Protein K48-linked Ubiquitination 2',3'-cyclic GMP-AMP Binding Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Protein Autoubiquitination Positive Regulation Of Chromatin Organization Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex ESCRT-0 Complex