SEC16A and MIA3

Number of citations of the paper that reports this interaction (PubMedID 28442536)
67

Data Source:
BioGRID (pull down)

		SEC16A	MIA3
Description		SEC16 homolog A, endoplasmic reticulum export factor	MIA SH3 domain ER export factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane Organelle Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	Protein Binding Cargo Receptor Activity
	Biological Process	Regulation Of COPII Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Endoplasmic Reticulum Organization Golgi Organization Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Substantia Nigra Development Protein Exit From Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Protein Stabilization Localization Within Membrane Protein Localization To Endoplasmic Reticulum Exit Site Protein Localization To Plasma Membrane	Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Leukocyte Migration Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Negative Regulation Of Cell Adhesion Protein Secretion Protein Transport Vesicle-mediated Transport Negative Regulation Of Cell Migration Vesicle Cargo Loading Wound Healing Lipoprotein Transport System Development Protein Localization To Endoplasmic Reticulum Exit Site COPII-coated Vesicle Cargo Loading Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways		COPII-mediated vesicle transport	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798 32041948) Eosinophil count ( 27863252) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 32888494) Serum alkaline phosphatase levels ( 33547301) Squamous cell carcinoma ( 31174203) Triglyceride levels ( 32154731) Ulcerative colitis ( 21297633 28067908)	Coronary artery disease ( 26343387 29212778 32469254 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 17634449 21378990) Myocardial infarction ( 26343387 33532862) Myocardial infarction (early onset) ( 19198609)
Interacting Genes		2 interacting genes: MIA3 SEC23A	17 interacting genes: CACNA1A CEP55 CLIC3 COL7A1 FXR2 HOMER3 HSD17B14 ITGAX LENG8 MTNR1B NCK2 PRDM14 SEC16A SEC23A SEC24C TRIM27 UBC
Entrez ID		9919	375056
HPRD ID		11075	18918
Ensembl ID		ENSG00000148396	ENSG00000154305
Uniprot IDs		A0A8I5KPG1 F1T0I1 O15027	Q5JRA6
PDB IDs			5KYN 5KYU 5KYW 7R3M
Enriched GO Terms of Interacting Partners?		COPII-coated Vesicle Cargo Loading Vesicle Cargo Loading Endoplasmic Reticulum Exit Site Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport COPII-coated Vesicle Budding Protein Localization To Endoplasmic Reticulum Exit Site COPII Vesicle Coat Lipoprotein Transport Negative Regulation Of Lymphocyte Migration Protein Localization To Endoplasmic Reticulum Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Vesicle Budding From Membrane Endoplasmic Reticulum Membrane Vesicle-mediated Transport COPII-coated ER To Golgi Transport Vesicle Intracellular Transport Protein Transport Cellular Response To Lipoprotein Particle Stimulus Cargo Receptor Activity Blood Vessel Endothelial Cell Migration Cellular Response To Low-density Lipoprotein Particle Stimulus Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Mononuclear Cell Migration Establishment Of Protein Localization Cellular Localization ER To Golgi Transport Vesicle Membrane Endoplasmic Reticulum Establishment Of Localization In Cell Endoplasmic Reticulum Organization Regulation Of Lymphocyte Migration Negative Regulation Of Leukocyte Migration Wound Healing Endothelial Cell Migration Intracellular Protein Localization Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Negative Regulation Of Leukocyte Cell-cell Adhesion	Endoplasmic Reticulum Exit Site ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat COPII-coated Vesicle Cargo Loading Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Cargo Loading
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