SV2B and HSFY1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SV2B	HSFY1
Description		synaptic vesicle glycoprotein 2B	heat shock transcription factor Y-linked 1
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Transmembrane Transporter Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Neurotransmitter Transport Chemical Synaptic Transmission Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type A (botA) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type E (botE)
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Gout (normal type) ( 32238385) Iris color (a* coordinate) ( 30895295) Iris color (b* coordinate) ( 30895295) Metabolite levels ( 19043545 23823483) Neuritic plaque ( 31497858) Primary sclerosing cholangitis ( 27992413) Rosacea symptom severity ( 29771307)
Interacting Genes		2 interacting genes: HSFY1 SYT1	20 interacting genes: ATXN1 BANP BPIFA1 CCNK DTX2 GCM2 HGS HNRNPF JAK2 NFYC OTUD7B QRICH1 RBFOX1 RBM47 RBPMS SMARCB1 SOX15 SV2B TBX6 TOX2
Entrez ID		9899	86614
HPRD ID		11765	11850
Ensembl ID		ENSG00000185518	ENSG00000172468
Uniprot IDs		Q7L1I2	Q96LI6
PDB IDs		8UO8 9F1R 9F2B 9F2J 9F2Y 9F3C
Enriched GO Terms of Interacting Partners?		Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Positive Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Syntaxin-3 Binding Positive Regulation Of Synaptic Vesicle Exocytosis Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Spontaneous Neurotransmitter Secretion Chromaffin Granule Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Dopamine Secretion Clathrin-sculpted Monoamine Transport Vesicle Membrane Calcium Ion-regulated Exocytosis Of Neurotransmitter Calcium-dependent Activation Of Synaptic Vesicle Fusion Positive Regulation Of Catecholamine Secretion Positive Regulation Of Neurotransmitter Secretion Neuron Projection Terminus Dense Core Granule Positive Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Dendrite Extension Detection Of Calcium Ion Calcium Ion Sensor Activity Positive Regulation Of Vesicle Fusion Syntaxin-1 Binding Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Low-density Lipoprotein Particle Receptor Binding Exocytic Vesicle Regulation Of Dopamine Secretion Protein Heterooligomerization Presynaptic Cytosol Postsynaptic Cytosol Excitatory Synapse Calcium-ion Regulated Exocytosis Regulation Of Vesicle Fusion Clathrin Binding Synaptic Vesicle Exocytosis Regulation Of Catecholamine Secretion Regulation Of Calcium Ion-dependent Exocytosis Neurotransmitter Secretion Presynaptic Active Zone Hippocampal Mossy Fiber To CA3 Synapse Syntaxin Binding Positive Regulation Of Regulated Secretory Pathway Calcium-dependent Phospholipid Binding Molecular Condensate Scaffold Activity Regulation Of Synaptic Vesicle Exocytosis Transport Vesicle Membrane Phosphatidylserine Binding Vesicle Docking	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleus Positive Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Metabolic Process Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Transcription By RNA Polymerase II Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Regulation Of G0 To G1 Transition Histone H3Y41 Kinase Activity Nuclear Receptor-mediated Mineralocorticoid Signaling Pathway Symbiont-induced Defense-related Programmed Cell Death Interleukin-35-mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Nucleic Acid Metabolic Process DNA-templated Transcription Regulation Of Postsynapse To Nucleus Signaling Pathway Mesoderm Development Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Immune Response In Nasopharyngeal-associated Lymphoid Tissue Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism RNA Processing Regulation Of Protein Kinase Activity Nucleobase-containing Compound Biosynthetic Process
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