ZSCAN18 and ZNF174

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZSCAN18	ZNF174
Description		zinc finger and SCAN domain containing 18	zinc finger protein 174
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Fibrillar Center Nucleus Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: APP EPM2AIP1 FDXACB1 HOXD4 LIG4 SAFB2 ZNF174 ZNF446 ZSCAN22	8 interacting genes: CDK6 MZF1 SCAND1 ZKSCAN8 ZNF20 ZNF24 ZSCAN18 ZSCAN22
Entrez ID		65982	7727
HPRD ID		07802	04876
Ensembl ID		ENSG00000121413	ENSG00000103343
Uniprot IDs		Q8TBC5	I3L2H2 Q15697
PDB IDs			1Y7Q
Enriched GO Terms of Interacting Partners?		DNA Binding Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Low-density Lipoprotein Particle Mediated Signaling DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation RRNA (uridine-N3-)-methyltransferase Activity Nucleus Central Nervous System Development Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Cell Activation Involved In Immune Response	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Zinc Ion Binding DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Nucleus Cyclin D2-CDK6 Complex Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Metal Ion Binding Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Type B Pancreatic Cell Development Lateral Ventricle Development Regulation Of Hematopoietic Stem Cell Differentiation
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